Cough Suppression: Dextromethorphan hydrobromide monohydrate is primarily used to relieve cough associated with various respiratory conditions, such as the common cold, flu, bronchitis, and upper respiratory tract infections. It works by suppressing the cough reflex in the brain, reducing the frequency and intensity of coughing episodes.
Antitussive Action: Dextromethorphan is classified as an antitussive, meaning it acts directly on the cough center in the brain to inhibit the cough reflex. Unlike opioid cough suppressants, such as codeine or hydrocodone, dextromethorphan does not have significant analgesic (pain-relieving) or addictive properties, making it a safer option for cough relief.
Non-Opioid Analgesic: While dextromethorphan is primarily used as a cough suppressant, it also exhibits mild analgesic (pain-relieving) properties at higher doses. However, these analgesic effects are generally weaker than those of opioid medications and are not typically the primary indication for dextromethorphan use.
Dosage Forms: Dextromethorphan hydrobromide monohydrate is available in various dosage forms, including oral solutions, syrups, tablets, capsules, and lozenges. The choice of dosage form depends on factors such as patient age, preference, and the severity of cough symptoms.
Robitussin and Other Brand Names: Dextromethorphan is commonly found in over-the-counter cough and cold medications, often under brand names such as Robitussin, Delsym, Vicks DayQuil Cough, and Mucinex DM. These products may contain dextromethorphan alone or in combination with other active ingredients such as guaifenesin (an expectorant) or pseudoephedrine (a decongestant).
Safety and Side Effects: Dextromethorphan is generally considered safe when used as directed, but like any medication, it can cause side effects in some individuals. Common side effects may include dizziness, drowsiness, nausea, vomiting, constipation, and stomach upset. Rare but potentially serious side effects may include allergic reactions, serotonin syndrome (especially when combined with certain other medications), and respiratory depression (in high doses).
Drug Interactions: Dextromethorphan may interact with certain medications, including monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and other drugs that affect serotonin levels in the brain. Combining dextromethorphan with these medications can increase the risk of serotonin syndrome, a potentially life-threatening condition characterized by changes in mental status, agitation, hallucinations, and autonomic instability.
Contraindications: Dextromethorphan is contraindicated in individuals with a known hypersensitivity or allergy to the medication or its components. It should not be used in children under certain ages or in individuals with certain medical conditions such as chronic cough (e.g., asthma, chronic bronchitis), severe respiratory depression, or gastrointestinal obstruction.
Bacteria Impacted by dextromethorphan hydrobromide monohydrate,(prescription)
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Impact of dextromethorphan hydrobromide monohydrate,(prescription) on Conditions from US National Library of Medicine
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups.
We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio: Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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