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Urinary Retention: Bethanechol chloride is commonly prescribed to treat urinary retention, a condition characterized by the inability to empty the bladder fully. It works by stimulating the muscles of the bladder, causing it to contract and expel urine. This medication is particularly useful in cases of postoperative urinary retention or urinary retention due to neurogenic bladder dysfunction.
Neurogenic Bladder: Neurogenic bladder is a dysfunction of the urinary bladder due to a neurological condition, such as spinal cord injury, multiple sclerosis, or Parkinson's disease. Bethanechol chloride may be used to improve bladder emptying in individuals with neurogenic bladder by increasing bladder muscle tone and promoting urination.
Bladder Atony: Bladder atony refers to a condition in which the bladder muscles become weak and lose their ability to contract effectively, leading to urinary retention. Bethanechol chloride can help improve bladder muscle tone and restore bladder function in individuals with bladder atony.
Urinary Incontinence: Although primarily used to treat urinary retention, bethanechol chloride may also have a role in managing certain types of urinary incontinence, particularly if the underlying cause is related to impaired bladder function. By enhancing bladder muscle contractions, it may help reduce episodes of urinary leakage.
Gastrointestinal Disorders: In addition to its effects on the bladder, bethanechol chloride may also stimulate gastrointestinal motility and increase gastric emptying. It has been used off-label to treat certain gastrointestinal disorders characterized by delayed gastric emptying or gastrointestinal dysmotility, such as gastroparesis.
Side Effects: Common side effects of bethanechol chloride include abdominal discomfort, cramps, diarrhea, nausea, and vomiting, which are primarily due to its gastrointestinal stimulatory effects. It may also cause headache, dizziness, sweating, and flushing. Rare but serious side effects include severe abdominal pain, urinary urgency, difficulty breathing, and irregular heartbeat.
Contraindications: Bethanechol chloride is contraindicated in individuals with a history of asthma, peptic ulcer disease, intestinal obstruction, or bladder obstruction. It should be used with caution in patients with cardiovascular diseases, as it can cause bradycardia (slow heart rate) and hypotension (low blood pressure).
Dosage and Administration: The dosage of bethanechol chloride varies depending on the individual's condition and response to treatment. It is usually taken orally, either with or without food, and the dose may be adjusted by a healthcare provider based on the patient's needs.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.