If you encounter any studies on PubMed that identifies additional biofilm busters, please forward to us. These should be items on our modifiers list.
| Substance | Sources |
|---|---|
| (2S)-2-amino-5-carbamimidamidopentanoic acid {arginine} |
๐
Biosurfactant complexed with arginine has antibiofilm activity against methicillin-resistant Staphylococcus aureus.
Future microbiology (Future Microbiol ) Vol: Issue: Pages: 1-13 Pub: 2024 Jun 12 ePub: 2024 Jun 12 Authors Dias Barroso FD,da Silva LJ,Queiroz HA,do Amaral Valente Sรก LG,da Silva AR,da Silva CR,de Andrade Neto JB,Cavalcanti BC,de Moraes MO,Pinazo A,Pรฉrez L,Nobre Jรบnior HV |
| 5,6-dihydroxy-7-O-glucuronide flavone {Baicalin } |
๐
Baicalein inhibits biofilm formation of avian pathogenic Escherichia coli in vitro mainly by affecting adhesion.
Research in veterinary science (Res Vet Sci ) Vol: 174 Issue: Pages: 105291 Pub: 2024 Jul ePub: 2024 May 7 Authors Liu W,Wang Y,Sun Y,Xia W,Qian X,Bo R,Huang Y,Ruan X |
| diclofenac sodium,(prescription) |
๐
Antibacterial and antibiofilm activities of diclofenac against levofloxacin-resistant Stenotrophomonas maltophilia isolates; emphasizing repurposing of diclofenac.
Iranian journal of microbiology (Iran J Microbiol ) Vol: 16 Issue: 2 Pages: 166-175 Pub: 2024 Apr ePub: Authors El-Soudany I,Abdelwahab IA,Yakout MA |
| diclofenac sodium,(prescription) |
๐
Diclofenac sodium effectively inhibits the biofilm formation of Staphylococcus epidermidis.
Archives of microbiology (Arch Microbiol ) Vol: 206 Issue: 7 Pages: 289 Pub: 2024 Jun 7 ePub: 2024 Jun 7 Authors Xi H,Luo Z,Liu MF,Chen Q,Zhu Q,Yuan L,Sheng YY,Zhao R |
| Dihydroquercetin {Taxifolin} |
๐
Taxifolin, an Inhibitor of Sortase A, Interferes With the Adhesion of Methicillin-Resistant Staphylococcal aureus.
Frontiers in microbiology (Front Microbiol ) Vol: 12 Issue: Pages: 686864 Pub: 2021 ePub: 2021 Jul 6 Authors Wang L,Wang G,Qu H,Wang K,Jing S,Guan S,Su L,Li Q,Wang D |
| doxycycline [CFS] |
๐
Synergistic effect of doxycycline and aqueous extract of irradiated khella on structure of nanobacteria isolated from kidney stones: In vitro and in vivo studies.
Cell biochemistry and function (Cell Biochem Funct ) Vol: 41 Issue: 8 Pages: 1275-1294 Pub: 2023 Dec ePub: 2023 Oct 5 Authors Fayez N,Ibrahim MK,Farrag HA,Mohamed MAEH,Tablawy SYE |
| Enterococcus faecalis {Streptococcus faecalis} |
๐
Selection of starter lactic acid bacteria capable of forming biofilms on wooden vat prototypes for their future application in traditional Sicilian goat`s milk cheese making.
International journal of food microbiology (Int J Food Microbiol ) Vol: 419 Issue: Pages: 110752 Pub: 2024 Jul 16 ePub: 2024 May 20 Authors Capri FC,Gaglio R,Botta L,Settanni L,Alduina R |
| eugenol {Eugenic acid} |
๐
Poloxamer-Based Mixed Micelles Loaded with Thymol or Eugenol for Topical Applications.
ACS omega (ACS Omega ) Vol: 9 Issue: 22 Pages: 23209-23219 Pub: 2024 Jun 4 ePub: 2024 May 20 Authors Sedlarikova J,Janalikova M,Egner P,Pleva P |
| Ginkgo biloba {Ginkgo} |
๐
Evaluation of the antimicrobial function of Ginkgo biloba exocarp extract against clinical bacteria and its effect on Staphylococcus haemolyticus by disrupting biofilms.
Journal of ethnopharmacology (J Ethnopharmacol ) Vol: 298 Issue: Pages: 115602 Pub: 2022 Nov 15 ePub: 2022 Aug 24 Authors Wang C,Wei PW,Song CR,Wang X,Zhu GF,Yang YX,Xu GB,Hu ZQ,Tang L,Liu HM,Wang B |
| Hibiscus {Rose mallow} |
๐
Medicinal herbs, especially Hibiscus sabdariffa, inhibit oral pathogenic bacteria.
Journal of oral biosciences (J Oral Biosci ) Vol: 66 Issue: 1 Pages: 179-187 Pub: 2024 Mar ePub: 2024 Jan 24 Authors Takada K,Nakano S,Nishio R,Muku D,Mochizuki S,Inui I,Okita K,Koga A,Watanabe K,Yoshioka Y,Ariyoshi W,Yamasaki R |
| Lacticaseibacillus rhamnosus {l. rhamnosus} |
๐
Evaluation of Anti-Bacterial and Anti-Biofilm Activity of Native Probiotic Strains of Lactobacillus Extracts.
Iranian biomedical journal (Iran Biomed J ) Vol: 28 Issue: 2&3 Pages: 102-12 Pub: 2023 Dec 17 ePub: 2023 Dec 17 Authors Karimzadeh Barenji E,Beglari S,Tahghighi A,Azerang P,Rohani M |
| Lactococcus lactis {Streptococcus lactis} |
๐
Selection of starter lactic acid bacteria capable of forming biofilms on wooden vat prototypes for their future application in traditional Sicilian goat`s milk cheese making.
International journal of food microbiology (Int J Food Microbiol ) Vol: 419 Issue: Pages: 110752 Pub: 2024 Jul 16 ePub: 2024 May 20 Authors Capri FC,Gaglio R,Botta L,Settanni L,Alduina R |
| Lumbrokinase |
๐
Ex Vivo Model to Evaluate the Antibacterial and Anti-Inflammatory Effects of Gelatin-Tricalcium Phosphate Composite Incorporated with Emodin and Lumbrokinase for Bone Regeneration.
Bioengineering (Basel, Switzerland) (Bioengineering (Basel) ) Vol: 10 Issue: 8 Pages: Pub: 2023 Jul 31 ePub: 2023 Jul 31 Authors Wang WL,Hsu YM,Lin ML,Chen SS,Lai YH,Huang CH,Yao CH |
| Menaquinone K2 {Vitamin K} |
๐
Vitamin D and vitamin K1 as novel inhibitors of biofilm in Gram-negative bacteria.
BMC microbiology (BMC Microbiol ) Vol: 24 Issue: 1 Pages: 173 Pub: 2024 May 18 ePub: 2024 May 18 Authors Lutfi LL,Shaaban MI,Elshaer SL |
| Moringa Oleifera |
๐
Antimicrobial Effect of Moringa Oleifera L. and Red Pomegranate against Clinically Isolated Porphyromonas gingivalis: in vitro Study.
Archives of Razi Institute (Arch Razi Inst ) Vol: 77 Issue: 4 Pages: 1405-1419 Pub: 2022 Aug ePub: 2022 Aug 31 Authors Faisal Madhloom A,Bashir Hashim Al-Taweel F,Sha AM,Raad Abdulbaqi H |
| Nattokinase {Natto} |
๐
Nattokinase, a Subtilisin-like Alkaline-Serine Protease, Reduces Mutacin Activity by Inactivating the Competence-Stimulating Peptide in Streptococcus mutans.
Pathogens (Basel, Switzerland) (Pathogens ) Vol: 13 Issue: 4 Pages: Pub: 2024 Mar 27 ePub: 2024 Mar 27 Authors Kimijima M,Narisawa N,Hori E,Mandokoro K,Ito T,Ota Y,Sashida M,Kawai Y,Takenaga F |
| Nattokinase {Natto} |
๐
An Essential Role for Coagulase in Staphylococcus aureus Biofilm Development Reveals New Therapeutic Possibilities for Device-Related Infections.
The Journal of infectious diseases (J Infect Dis ) Vol: 212 Issue: 12 Pages: 1883-93 Pub: 2015 Dec 15 ePub: 2015 Jun 4 Authors Zapotoczna M,McCarthy H,Rudkin JK,O`Gara JP,O`Neill E |
| Nigella sativa {black cumin} |
๐
Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.).
Drug design, development and therapy (Drug Des Devel Ther ) Vol: 18 Issue: Pages: 1917-1932 Pub: 2024 ePub: 2024 May 29 Authors Kurnia D,Padilah R,Apriyanti E,Dharsono HDA |
| Olea europaea {Olive leaf} |
๐
Antimicrobial and anti-biofilm properties of oleuropein against Escherichia coli and fluconazole-resistant isolates of Candida albicans and Candida glabrata.
BMC microbiology (BMC Microbiol ) Vol: 24 Issue: 1 Pages: 154 Pub: 2024 May 4 ePub: 2024 May 4 Authors Esfandiary MA,Khosravi AR,Asadi S,Nikaein D,Hassan J,Sharifzadeh A |
| origanum vulgare {oregano} |
๐
Inย vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI.
Anaerobe (Anaerobe ) Vol: 76 Issue: Pages: 102604 Pub: 2022 Aug ePub: 2022 Jun 14 Authors Aleksic A,Stojanovic-Radic Z,Harmanus C,Kuijper EJ,Stojanovic P |
| Pentadigalloylglucose {Tannic Acid} |
๐
Tannic acid inhibits Escherichia coli biofilm formation and underlying molecular mechanisms: Biofilm regulator CsgD.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (Biomed Pharmacother ) Vol: 175 Issue: Pages: 116716 Pub: 2024 Jun ePub: 2024 May 11 Authors Long J,Yang C,Liu J,Ma C,Jiao M,Hu H,Xiong J,Zhang Y,Wei W,Yang H,He Y,Zhu M,Yu Y,Fu L,Chen H |
| Pentahydroxypentane {Xylitol} |
๐
Biofilm biomass disruption by natural substances with potential for endodontic use.
Brazilian oral research (Braz Oral Res ) Vol: 27 Issue: 1 Pages: 20-5 Pub: 2013 Jan-Feb ePub: Authors Alves FR,Silva MG,Rรดรงas IN,Siqueira JF Jr |
| Piper nigrum {black pepper} |
๐
Evaluation of Anti-Candida Potential of Piper nigrum Extract in Inhibiting Growth, Yeast-Hyphal Transition, Virulent Enzymes, and Biofilm Formation.
Journal of fungi (Basel, Switzerland) (J Fungi (Basel) ) Vol: 8 Issue: 8 Pages: Pub: 2022 Jul 27 ePub: 2022 Jul 27 Authors Bravo-Chaucanรฉs CP,Vargas-Casanova Y,Chitiva-Chitiva LC,Ceballos-Garzon A,Modesti-Costa G,Parra-Giraldo CM |
| Piper nigrum {black pepper} |
๐
Inย vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI.
Anaerobe (Anaerobe ) Vol: 76 Issue: Pages: 102604 Pub: 2022 Aug ePub: 2022 Jun 14 Authors Aleksic A,Stojanovic-Radic Z,Harmanus C,Kuijper EJ,Stojanovic P |
| Punica granatum {pomegranate} |
๐
Antimicrobial Effect of Moringa Oleifera L. and Red Pomegranate against Clinically Isolated Porphyromonas gingivalis: in vitro Study.
Archives of Razi Institute (Arch Razi Inst ) Vol: 77 Issue: 4 Pages: 1405-1419 Pub: 2022 Aug ePub: 2022 Aug 31 Authors Faisal Madhloom A,Bashir Hashim Al-Taweel F,Sha AM,Raad Abdulbaqi H |
| Serrapeptase |
๐
An up-to-date review of biomedical applications of serratiopeptidase and its biobetter derivatives as a multi-potential metalloprotease.
Archives of microbiology (Arch Microbiol ) Vol: 206 Issue: 4 Pages: 180 Pub: 2024 Mar 19 ePub: 2024 Mar 19 Authors Hosseini SB,Azizi M,Nojoumi SA,Valizadeh V |
| Serrapeptase |
๐
Preparation and Physicochemical Characterization of Hyaluronic Acid-Lysine Nanogels Containing Serratiopeptidase to Control Biofilm Formation.
Scientific reports (Sci Rep ) Vol: 14 Issue: 1 Pages: 6111 Pub: 2024 Mar 13 ePub: 2024 Mar 13 Authors Mahdiani H,Yazdani F,Khoramipour M,Valizadeh V,Bakhshandeh H,Dinarvand R |
| Serrapeptase |
๐
In vitro and in silico evaluation of the serrapeptase effect on biofilm and amyloids of Pseudomonas aeruginosa.
Applied microbiology and biotechnology (Appl Microbiol Biotechnol ) Vol: 107 Issue: 23 Pages: 7269-7285 Pub: 2023 Dec ePub: 2023 Sep 23 Authors Katsipis G,Avgoulas DI,Geromichalos GD,Petala M,Pantazaki AA |
| Serrapeptase |
๐
Improved anti-biofilm activity and long-lasting effects of novel serratiopeptidase immobilized on cellulose nanofibers.
Applied microbiology and biotechnology (Appl Microbiol Biotechnol ) Vol: 107 Issue: 21 Pages: 6487-6496 Pub: 2023 Nov ePub: 2023 Sep 6 Authors Rouhani M,Valizadeh V,Bakhshandeh H,Hosseinzadeh SA,Molasalehi S,Atyabi SM,Norouzian D |
| Serrapeptase |
๐
Serrapeptase impairs biofilm, wall, and phospho-homeostasis of resistant and susceptible Staphylococcus aureus.
Applied microbiology and biotechnology (Appl Microbiol Biotechnol ) Vol: 107 Issue: 4 Pages: 1373-1389 Pub: 2023 Feb ePub: 2023 Jan 13 Authors Katsipis G,Pantazaki AA |
| Serrapeptase |
๐
Novel serratiopeptidase exhibits different affinities to the substrates and inhibitors.
Chemical biology & drug design (Chem Biol Drug Des ) Vol: 100 Issue: 4 Pages: 553-563 Pub: 2022 Oct ePub: 2022 Jul 1 Authors Hosseinzadeh SA,Valizadeh V,Rouhani M,Mirkazemi S,Azizi M,Norouzian D,Ahangari Cohan R |
| ß-(1?4)-linked D-glucosamine and N-acetyl-D-glucosamine {Chitosan} |
๐
Chitosan/cyclodextrin surface-adsorbed naringenin-loaded nanocapsules enhance bacterial quorum quenching and anti-biofilm activities.
Colloids and surfaces. B, Biointerfaces (Colloids Surf B Biointerfaces ) Vol: 211 Issue: Pages: 112281 Pub: 2022 Mar ePub: 2021 Dec 9 Authors Nguyen HT,Hensel A,Goycoolea FM |
| ß-(1?4)-linked D-glucosamine and N-acetyl-D-glucosamine {Chitosan} |
๐
Exploring the antimicrobial potential of chitosan nanoparticles: synthesis, characterization and impact on Pseudomonas aeruginosa virulence factors.
Nanoscale advances (Nanoscale Adv ) Vol: 6 Issue: 12 Pages: 3093-3105 Pub: 2024 Jun 11 ePub: 2024 Apr 22 Authors Marลกรญk D,Matรกtkovรก O,Kolkovรก A,Masรกk J |
| Thymus vulgaris {thyme} |
๐
Chemical Composition, Antioxidant, and Antibiofilm Properties of Essential Oil from Thymus capitatus Plants Organically Cultured on the Greek Island of Lemnos.
Molecules (Basel, Switzerland) (Molecules ) Vol: 28 Issue: 3 Pages: Pub: 2023 Jan 24 ePub: 2023 Jan 24 Authors Maniki E,Kostoglou D,Paterakis N,Nikolaou A,Kourkoutas Y,Papachristoforou A,Giaouris E |
| Thymus vulgaris {thyme} |
๐
Poloxamer-Based Mixed Micelles Loaded with Thymol or Eugenol for Topical Applications.
ACS omega (ACS Omega ) Vol: 9 Issue: 22 Pages: 23209-23219 Pub: 2024 Jun 4 ePub: 2024 May 20 Authors Sedlarikova J,Janalikova M,Egner P,Pleva P |
| vitamin d |
๐
Vitamin D and vitamin K1 as novel inhibitors of biofilm in Gram-negative bacteria.
BMC microbiology (BMC Microbiol ) Vol: 24 Issue: 1 Pages: 173 Pub: 2024 May 18 ePub: 2024 May 18 Authors Lutfi LL,Shaaban MI,Elshaer SL |
