Babesia ovis Details: NCBI 5869, gram-negative or unknown [species]
Fever: Babesia ovis infections typically result in fever as one of the initial symptoms. Fever is the result of the host's immune response to the presence of the parasite.
Anemia: Babesia ovis parasites infect and destroy red blood cells, leading to hemolytic anemia. Anemia can cause weakness, lethargy, pale mucous membranes, and in severe cases, jaundice.
Hemoglobinuria: Hemolysis of red blood cells can result in the release of hemoglobin into the bloodstream, leading to the presence of hemoglobin in the urine (hemoglobinuria). This can give the urine a red or brown color.
Jaundice: Severe hemolysis can lead to elevated levels of bilirubin in the blood, causing jaundice (yellowing of the skin, mucous membranes, and sclera).
Lethargy and Weakness: Infected sheep may exhibit lethargy, weakness, and reluctance to engage in physical activity due to the effects of anemia and the overall impact of the disease on their health.
Decreased Appetite: Babesia ovis infections can lead to a decreased appetite in sheep, resulting in reduced food intake and weight loss over time.
Enlarged Lymph Nodes and Spleen: Sheep with babesiosis may have enlarged lymph nodes (lymphadenopathy) and an enlarged spleen (splenomegaly) due to the involvement of these organs in the immune response to the infection.
Respiratory Distress: In severe cases, babesiosis can lead to respiratory distress, characterized by rapid or labored breathing, coughing, and difficulty breathing.
Neurological Signs: In some cases, particularly with severe infections, neurological signs such as ataxia, tremors, and convulsions may occur.
Abortion and Reproductive Problems: In pregnant ewes, Babesia ovis infections can lead to abortion, stillbirths, or weak lambs.
Death: In severe and untreated cases, babesiosis can lead to death, especially in young lambs or sheep with weakened immune systems.
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