Brachyspira hyodysenteriae Details: NCBI 159, gram-negative or unknown [species]

| ATCC 27164| Brachyspira hyodysenteriae| Brachyspira hyodysenteriae (Harris et al. 1972) Ochiai et al. 1998| CCUG 46668| NCTC 13041| Serpulina hyodysenteriae| Serpulina hyodysenteriae (Harris et al. 1972) Stanton 1992| strain B78| Treponema hyodysenteriae| Treponema hyodysenteriae Harris et al. 1972 (Approved Lists 1980)

1. Swine Dysentery: Brachyspira hyodysenteriae is the primary causative agent of swine dysentery, also known as bloody scours or hemorrhagic colitis in pigs. This disease is characterized by severe diarrhea, often containing blood and mucus, along with weight loss, dehydration, and decreased feed intake. Swine dysentery can lead to substantial economic losses in pig production due to reduced growth rates, increased mortality, and costs associated with treatment and control measures.

2. Colonization of the Large Intestine: Brachyspira hyodysenteriae colonizes the large intestine (specifically the colon) of pigs, where it adheres to and damages the colonic mucosa, leading to inflammation and diarrhea. The bacteria produce toxins and enzymes that contribute to the pathological changes observed in the intestinal mucosa and the clinical signs of swine dysentery.

3. Transmission: Swine dysentery is highly contagious and spreads among pigs through the fecal-oral route, primarily via direct contact with infected feces or contaminated environments. The bacteria can survive in feces and the environment for extended periods, facilitating transmission within and between pig herds.

4. Impact on Production and Welfare: Swine dysentery can have significant negative impacts on pig health, production, and welfare. Infected pigs experience discomfort and pain due to the severity of diarrhea and colonic inflammation, leading to reduced performance, compromised welfare, and increased susceptibility to other diseases.

5. Control and Management: Control of swine dysentery typically involves a combination of management practices, biosecurity measures, and antimicrobial treatment. Strategies may include strict hygiene protocols, segregation and isolation of affected animals, sanitation of facilities, and targeted use of antimicrobials to control outbreaks and reduce bacterial shedding. However, antimicrobial resistance in Brachyspira hyodysenteriae has become a concern, highlighting the importance of judicious antibiotic use and alternative control strategies.

Visuals of Interactions with other bacteria of the same rank

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

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Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Brachyspira hyodysenteriae

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	0.26			1	200	0	270	82.2	45	95.9	1	200	12.5 %ile	75 %ile
thorne	31.03			1	68	0	68	15.9	3	26.3	1	68	9.1 %ile	81.8 %ile

External Reference Ranges for Brachyspira hyodysenteriae

Brachyspira hyodysenteriae (NCBI 159) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
Thorne (20/80%ile)	0	2.06	0	0.0002
PrecisionBiome	2.4040986318141222E-05	9.694175969343632E-05	0	0

Statistic by Lab Source for Brachyspira hyodysenteriae

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
CerbaLab	33.333 %	0 %	%	1.0	3
es-xenogene	15.625 %	0.01 %	0.01 %	5.0	32
Thorne	21.649 %	0 %	0.001 %	63.0	291

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General Substance	Specific Substance	Effect
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