Rothia dentocariosa Details: NCBI 2047, high G+C gram-positive [species]

Found in Oral Cavity

For the possible significance see Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes, 2024

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| "Actinomyces dentocariosus" Onishi 1949| "Nocardia dentocariosus" (sic) (Onishi 1949) Roth 1957| "Nocardia salivae" Davis and Freer 1960| Actinomyces dentocariosus| ATCC 17931| CCUG 35437| CIP 81.83| DSM 43762| DSM 46363| IFO 12531| JCM 3067| NBRC 12531| NCTC 10917| Nocardia dentocariosus| Nocardia salivae| NRRL B-8017| Rothia denticariosa| Rothia dentocariosa| Rothia dentocariosa (Onishi 1949) Georg and Brown 1967 (Approved Lists 1980) emend. Daneshvar et al. 2004

1. Antibiotic Production: Streptomyces lincolnensis produces lincomycin, a lincosamide antibiotic. Lincomycin is effective against a wide range of Gram-positive bacteria, including staphylococci, streptococci, and anaerobic bacteria. It is used clinically to treat various infections, including skin and soft tissue infections, respiratory tract infections, and infections caused by anaerobic bacteria.

2. Clinical Applications: Lincomycin, produced by Streptomyces lincolnensis, has been used clinically for many years to treat bacterial infections in humans and animals. However, its use is now more limited due to the availability of other antibiotics and concerns about antibiotic resistance and side effects.

3. Antibiotic Resistance Studies: Streptomyces lincolnensis and its antibiotic, lincomycin, have been studied in the context of antibiotic resistance. Understanding the mechanisms of action and resistance to lincomycin can provide insights into combating antibiotic resistance in bacteria.

4. Biotechnological Applications: Lincomycin and its derivatives may have various biotechnological applications beyond medicine. They may be used in agriculture as growth promoters for livestock or in industry for the production of semi-synthetic antibiotics.

5. Environmental Health: Streptomyces lincolnensis, like other Streptomyces species, plays roles in soil ecology and nutrient cycling, which indirectly impact human health through ecosystem services such as soil fertility and environmental sustainability.

Visuals of Interactions with other bacteria of the same rank

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Rothia dentocariosa

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	0.62			5	180	0	129	38.6	28	46	5	180	6.3 %ile	87.5 %ile
biomesight	4.95	0	0	10	17299	0	3300	180.4	20	1591.6	0	40	0 %ile	100 %ile
thorne	96.55			1	36	0	30	11	7	9.5	0	24	0 %ile	100 %ile
thryve	6.23	0	0	5	570	0	181	41	26	71.5	8	56	0 %ile	100 %ile
ubiome	3.68			18	1735	0	881	135.6	30	380.5	14	50	0 %ile	100 %ile

External Reference Ranges for Rothia dentocariosa

Rothia dentocariosa (NCBI 2047) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
PrecisionBiome	2.2821770471637137E-05	0.0007013946888037026	0	0
Thorne (20/80%ile)	0.29	3.76	0	0.0004

Statistic by Lab Source for Rothia dentocariosa

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
BiomeSight	4.875 %	0.012 %	0.116 %	221.0	4533
CerbaLab	66.667 %	0.005 %	0.006 %	2.0	3
CosmosId	18.75 %	0.005 %	0.006 %	6.0	32
custom	2.74 %	0.002 %	0.002 %	2.0	73
es-xenogene	9.375 %	0.003 %	0.002 %	3.0	32
Medivere	12.5 %	0.002 %	%	1.0	8
Precision	25 %	0 %	%	1.0	4
Thorne	82.562 %	0.001 %	0.002 %	232.0	281
Thryve	7.083 %	0.004 %	0.008 %	109.0	1539
uBiome	3.625 %	0.014 %	0.038 %	29.0	800

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Common and OTC Supplements	acetylsalicylic acid,aspirin	1 Studies recorded. The consensus is Increases📓, Click for details.
Common and OTC Supplements	long-term, moderate-intensity exercise {exercise}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Cannabis sativa seed oil {Hemp Oil}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Honey {Honey }	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Nicotine, Nicotine Patch	2 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Punica granatum {pomegranate}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice	Azadirachta indica {Neem}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Miscellaneous, food additives, and other odd items	Below normal temperature {Cold exposure}	1 Studies recorded. The consensus is Increases📓, Click for details.
Not Classified	Mycotoxins {Home Dampness}	1 Studies recorded. The consensus is Increases👶, Click for details.
Not Classified	Nitrogen Oxide x Particulate Matter {Urban air pollutant}	1 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	Bacteriophages LH01,T4D,LL12,LL5 {PreforPro}	1 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	Human milk oligosaccharides (prebiotic, Holigos, Stachyose)	2 Studies recorded. The consensus is Decreases👶📓, Click for details.
Prebiotics and similar	oligosaccharides {oligosaccharides}	2 Studies recorded. The consensus is Decreases👶📓, Click for details.
Prescription - Other	econazole nitrate,(prescription)	1 Studies recorded. The consensus is Increases📓, Click for details.
Prescription - Other	proton-pump inhibitors (prescription)	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	Bifidobacterium animalis {B. animalis}	1 Studies recorded. The consensus is Decreases📓, Click for details.

Foods Containing the Rothia dentocariosa bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Dehulled maize dough, Ghana Weight: 0.2542 Swiss-Dutch-type cheese Weight: 0.09207 Dehulled maize dough fermented 12h, Ghana Weight: 0.0503