Spirochaetales Details: NCBI 136, gram-negative or unknown [order]

| Spirochaetales| Spirochaetales Buchanan 1917 (Approved Lists 1980) emend. Gupta et al. 2013| spirochetes

1. Pathogenic Spirochetes:

   • Some spirochetes within the order Spirochaetales are known to be pathogenic and can cause diseases in humans and animals. Notable examples include:
     • Borrelia burgdorferi: Causes Lyme disease, which is transmitted through the bite of infected ticks.
     • Treponema pallidum: Causes syphilis, a sexually transmitted infection.
     • Leptospira spp.: Cause leptospirosis, a bacterial infection that can be transmitted through contact with contaminated water or soil.

2. Commensal and Environmental Spirochetes:

   • Not all spirochetes within the order Spirochaetales are pathogenic. Some are part of the normal microbial flora in the gastrointestinal tracts of animals, including humans, and contribute to various ecological processes.

3. Lyme Disease:

   • Lyme disease, caused by Borrelia burgdorferi and transmitted by ticks, is a well-known spirochetal infection. It can lead to symptoms such as fever, fatigue, joint pain, and skin rashes. If left untreated, Lyme disease can progress to more severe complications.

4. Syphilis:

   • Treponema pallidum, the spirochete responsible for syphilis, can cause a range of symptoms, including sores, rashes, and systemic involvement. If not treated, syphilis can progress to more serious stages affecting multiple organs.

5. Leptospirosis:

   • Leptospirosis, caused by various Leptospira species, can lead to flu-like symptoms and, in severe cases, affect the liver, kidneys, and other organs. It is often associated with exposure to water or soil contaminated with the urine of infected animals.

Visuals of Interactions with other bacteria of the same rank

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Spirochaetales

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	1.5			6	17780	0	14140	2690.5	285	5841.5	0	1480	0 %ile	100 %ile
biomesight	23.3	0	10	10	130	0	26304	1207.6	30	12804.5	10	70	0 %ile	93.9 %ile
thorne	100			41	281	0	261	129.4	107	66.9	71	249	0 %ile	100 %ile
thryve	9.3	0	0	7	1020	0	233	35.5	21	100.7	7	35	0 %ile	100 %ile
ubiome	1.52			51	5232	0	5505	1638	1024	1973.2	51	5232	7.1 %ile	85.7 %ile

External Reference Ranges for Spirochaetales

Spirochaetales (NCBI 136) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
PrecisionBiome	0.00010624698188621551	0.003229329129680991	0	0
Thorne (20/80%ile)	52.99	98.45	0.0053	0.0098

Statistic by Lab Source for Spirochaetales

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
BiomeSight	24.329 %	0.091 %	1.223 %	1079.0	4435
BiomeSightRdp	12.903 %	0.002 %	0.003 %	4.0	31
CerbaLab	100 %	0.053 %	0.036 %	3.0	3
custom	34.247 %	0.86 %	0.851 %	25.0	73
es-xenogene	78.125 %	0.041 %	0.034 %	25.0	32
Medivere	12.5 %	0.001 %	%	1.0	8
Thorne	93.75 %	0.006 %	0.004 %	255.0	272
Thryve	11.922 %	0.006 %	0.043 %	183.0	1535
Tiny	14.286 %	0.005 %	%	1.0	7
uBiome	1.504 %	0.164 %	0.197 %	12.0	798
vitract	100 %	0.004 %	0.004 %	2.0	2

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Antibiotics, Antivirals etc	amoxicillin [CFS]	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	ceftriaxone	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	doxycycline [CFS]	1 Studies recorded. The consensus is Decreases👪, Click for details.
Common and OTC Supplements	5-Hydroxytryptophan {5-HTP}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Citrus limon {Lemon}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	henopodium quinoa {Quinoa}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Vitamins, Minerals and similar	Mixture of Vitamin B? {B Vitamins}	1 Studies recorded. The consensus is Increases📓, Click for details.
Vitamins, Minerals and similar	nicotinic acid {Vitamin B-3}	1 Studies recorded. The consensus is Increases📓, Click for details.