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Psoriasis Treatment: Calcipotriene is a synthetic form of vitamin D3 that helps to regulate skin cell growth and differentiation. It is applied topically to psoriatic lesions to slow down the excessive proliferation of skin cells and reduce inflammation, leading to improvement in the appearance and symptoms of psoriasis.
Reduction of Plaque Formation: Psoriasis is characterized by the formation of thickened, scaly plaques on the skin. Calcipotriene helps to reduce the thickness and scaling of these plaques, leading to smoother skin and reduced itchiness and discomfort.
Anti-inflammatory Effects: Calcipotriene has anti-inflammatory properties that help to alleviate redness, swelling, and irritation associated with psoriatic lesions. It helps to calm the immune response in the skin, thereby reducing the severity of psoriasis symptoms.
Promotion of Normal Skin Turnover: In psoriasis, skin cells reproduce at an accelerated rate, leading to the buildup of thick, scaly patches. Calcipotriene normalizes the turnover of skin cells by promoting their maturation and
Rank | Probiotic | Impact |
---|---|---|
genus | Bifidobacterium | Reduces |
species | Akkermansia muciniphila | Reduces |
species | Bacteroides uniformis | Reduces |
species | Bifidobacterium adolescentis | Reduces |
species | Bifidobacterium longum | Reduces |
species | Escherichia coli | Reduces |
species | Parabacteroides distasonis | Reduces |
subspecies | Bifidobacterium longum subsp. infantis | Reduces |
subspecies | Bifidobacterium longum subsp. longum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Taxonomy | Rank | Effect | Citations | Notation |
---|---|---|---|---|
[Ruminococcus] torques | species | Decreases | π Source Study | |
Agathobacter | genus | Decreases | πͺ Source Study | |
Agathobacter rectalis | species | Decreases | π Source Study | |
Akkermansia | genus | Decreases | π Source Study | |
Akkermansia glycaniphila | species | Decreases | πΆ Source Study | |
Akkermansia massiliensis | species | Decreases | πΆ Source Study | |
Akkermansia muciniphila | species | Decreases | π Source Study | High Levels linked to long-lived individuals |
Akkermansiaceae | family | Decreases | πͺ Source Study | |
Bacteroides | genus | Decreases | πͺ Source Study | |
Bacteroides caccae | species | Decreases | π Source Study | |
Bacteroides fragilis | species | Decreases | π Source Study | H02076 Bacteroides infection |
Bacteroides ovatus | species | Decreases | π Source Study | |
Bacteroides thetaiotaomicron | species | Decreases | π Source Study | |
Bacteroides uniformis | species | Decreases | π Source Study | Infectious bacteria |
Bacteroides xylanisolvens | species | Decreases | π Source Study |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 0.5 | 0.5 | |
Acne | 0.6 | 0.9 | -0.5 |
ADHD | 3.9 | 0.6 | 5.5 |
Age-Related Macular Degeneration and Glaucoma | 1.1 | 0.4 | 1.75 |
Allergic Rhinitis (Hay Fever) | 3 | 2.2 | 0.36 |
Allergies | 5.5 | 3.5 | 0.57 |
Allergy to milk products | 1.8 | 1.6 | 0.13 |
Alopecia (Hair Loss) | 1.2 | 1.2 | |
Alzheimer's disease | 4.9 | 6.4 | -0.31 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | 3.5 | 0.8 | 3.38 |
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