Lowering Blood Pressure: Labetalol works by blocking both beta receptors and alpha receptors. By doing so, it reduces the force and rate of heart contractions, as well as dilates blood vessels, leading to decreased blood pressure. Controlling hypertension with labetalol helps reduce the risk of cardiovascular events such as stroke, heart attack, and heart failure.
Management of Hypertensive Emergencies: Labetalol is often used in the management of hypertensive emergencies, where blood pressure is severely elevated and requires rapid reduction to prevent organ damage. Its dual action on both alpha and beta receptors makes it effective in quickly lowering blood pressure in these critical situations.
Angina Pectoris: Labetalol may also be used in the treatment of angina pectoris, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart muscle. By reducing the heart's workload and oxygen demand, labetalol helps alleviate symptoms of angina and improves exercise tolerance.
Heart Failure: In some cases, labetalol may be prescribed as adjunctive therapy in the management of heart failure. By reducing the heart's workload and improving cardiac output, labetalol can help alleviate symptoms and improve quality of life in patients with heart failure.
Atrial Fibrillation: Labetalol may be used to control heart rate in patients with atrial fibrillation or atrial flutter, irregular heart rhythms characterized by rapid and chaotic electrical activity in the upper chambers of the heart. By slowing down the heart rate, labetalol helps improve cardiac function and reduce symptoms associated with these arrhythmias.
Migraine Prophylaxis: Labetalol has been used off-label for the prophylactic treatment of migraine headaches. Its ability to block beta receptors may help prevent migraine attacks by stabilizing blood vessels in the brain and reducing the release of neurotransmitters involved in migraine pathophysiology.
Pheochromocytoma: Labetalol may be used to manage hypertension associated with pheochromocytoma, a rare tumor of the adrenal glands that produces excess catecholamines (adrenaline and noradrenaline). By blocking the effects of these hormones on the cardiovascular system, labetalol helps control blood pressure and stabilize the patient before surgery to remove the tumor.
Bacteria Impacted by labetalol hydrochloride,(prescription)
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Impact of labetalol hydrochloride,(prescription) on Conditions from US National Library of Medicine
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups.
We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio: Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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