🍽️ fluoroquinolone

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  1. Respiratory Tract Infections: Fluoroquinolones are frequently prescribed to treat respiratory tract infections, including acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia.

  2. Urinary Tract Infections (UTIs): Fluoroquinolones are often used as a first-line treatment for uncomplicated and complicated UTIs caused by susceptible bacteria.

  3. Skin and Soft Tissue Infections: Fluoroquinolones are effective against skin and soft tissue infections, such as cellulitis, abscesses, and wound infections caused by susceptible bacteria.

  4. Bone and Joint Infections: Fluoroquinolones may be used to treat bone and joint infections, including osteomyelitis and septic arthritis, in combination with other antibiotics.

  5. Gastrointestinal Infections: Fluoroquinolones can be prescribed for gastrointestinal infections, including infectious diarrhea caused by certain bacterial pathogens such as E. coli, Salmonella, and Shigella species.

  6. Sexually Transmitted Infections (STIs): Fluoroquinolones were previously used to treat STIs such as gonorrhea and chlamydia, but their use has decreased due to increasing antibiotic resistance.

  7. Intra-abdominal Infections: Fluoroquinolones are sometimes used to treat intra-abdominal infections, including peritonitis and abscesses, in combination with other antibiotics.

  8. Systemic Infections: Fluoroquinolones can be used to treat systemic infections, such as sepsis or bloodstream infections, caused by susceptible bacteria.

  9. Chronic Bacterial Prostatitis: Fluoroquinolones are one of the treatment options for chronic bacterial prostatitis caused by susceptible bacteria.

  10. Prevention of Infections: In certain cases, fluoroquinolones may be used prophylactically to prevent bacterial infections, such as in patients undergoing certain surgical procedures or those with compromised immune systems.

  11. Adverse Effects: Fluoroquinolones can cause various adverse effects, including gastrointestinal symptoms (nausea, vomiting, diarrhea), central nervous system effects (headache, dizziness, confusion), tendonitis, tendon rupture, QT interval prolongation, phototoxicity, and allergic reactions.

  12. Antibiotic Resistance: Overuse or misuse of fluoroquinolones can contribute to the development of antibiotic-resistant bacterial strains.

  13. Drug Interactions: Fluoroquinolones may interact with other medications, including antacids, sucralfate, certain anticoagulants, and corticosteroids.

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⚗️ Compensation for antibiotic usage

Data Contradictions — Limits of Certainity

Impacted of fluoroquinolone On Probiotics

Bacteria Impacted by fluoroquinolone

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

Impact of fluoroquinolone on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

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