AI Engines For more Details: Perplexity Kagi Labs You
Menopausal Symptoms Relief: Like other forms of estrogen, equilin was primarily used to relieve symptoms of menopause, including hot flashes, night sweats, vaginal dryness, and mood changes. Estrogen helps to alleviate these symptoms by replenishing declining hormone levels in menopausal and postmenopausal women.
Prevention of Osteoporosis: Estrogen has a protective effect on bone health, and HRT with equilin was sometimes prescribed to help prevent osteoporosis and reduce the risk of fractures in postmenopausal women.
Genitourinary Health: Estrogen therapy, including equilin, can help maintain the health of the genitourinary tract by preventing vaginal dryness, discomfort during intercourse, and urinary symptoms such as urgency and frequency.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Bacteroides uniformis | Reduces |
| species | Escherichia coli | Reduces |
| species | Lacticaseibacillus paracasei | Reduces |
| species | Parabacteroides distasonis | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| ADHD | 2.5 | 0.6 | 3.17 |
| Age-Related Macular Degeneration and Glaucoma | 1.1 | 0.4 | 1.75 |
| Allergic Rhinitis (Hay Fever) | 2.5 | 1.2 | 1.08 |
| Allergies | 3.3 | 1.5 | 1.2 |
| Allergy to milk products | 1.9 | 1.3 | 0.46 |
| Alopecia (Hair Loss) | 1.1 | 1.1 | |
| Alzheimer's disease | 4.6 | 3.4 | 0.35 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 2 | 0.8 | 1.5 |
| Ankylosing spondylitis | 3 | 0.9 | 2.33 |
| Anorexia Nervosa | 1.4 | 2.3 | -0.64 |
| Antiphospholipid syndrome (APS) | 0.8 | 0.8 | |
| Asthma | 4.2 | 1.1 | 2.82 |
| Atherosclerosis | 1.9 | 0.9 | 1.11 |
| Atrial fibrillation | 2.5 | 1.5 | 0.67 |
| Autism | 6.9 | 5.4 | 0.28 |
| Autoimmune Disease | 0.9 | 0.7 | 0.29 |
| Barrett esophagus cancer | 0.3 | 0.3 | 0 |
| benign prostatic hyperplasia | 0.6 | 0.3 | 1 |
| Biofilm | 1.8 | 1.8 | |
| Bipolar Disorder | 2.1 | 1.4 | 0.5 |
| Brain Trauma | 0.6 | 1.1 | -0.83 |
| Breast Cancer | 1.1 | 1.1 | |
| Cancer (General) | 0.6 | 0.6 | 0 |
| Carcinoma | 4.4 | 2.3 | 0.91 |
| Celiac Disease | 1.7 | 2 | -0.18 |
| Cerebral Palsy | 0.8 | 1.3 | -0.63 |
| Chronic Fatigue Syndrome | 3.6 | 3.6 | 0 |
| Chronic Kidney Disease | 2.7 | 1.4 | 0.93 |
| Chronic Lyme | 0.8 | -0.8 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 2.3 | 1.4 | 0.64 |
| Chronic Urticaria (Hives) | 1.6 | 0.5 | 2.2 |
| Coagulation / Micro clot triggering bacteria | 1.8 | 1.3 | 0.38 |
| Cognitive Function | 2.2 | 1.3 | 0.69 |
| Colorectal Cancer | 6.4 | 2.1 | 2.05 |
| Constipation | 1.3 | 0.7 | 0.86 |
| Coronary artery disease | 2 | 1.8 | 0.11 |
| COVID-19 | 5.7 | 5.3 | 0.08 |
| Crohn's Disease | 6.6 | 3.7 | 0.78 |
| Cushing's Syndrome (hypercortisolism) | 0.4 | -0.4 | |
| cystic fibrosis | 1.1 | 1 | 0.1 |
| d-lactic acidosis (one form of brain fog) | 0.5 | 0.5 | |
| deep vein thrombosis | 2.2 | 1.4 | 0.57 |
| Denture Wearers Oral Shifts | 1.4 | 1.4 | |
| Depression | 7.3 | 5.3 | 0.38 |
| Dermatomyositis | 0.3 | 0.3 | |
| Eczema | 1.4 | 1.3 | 0.08 |
| Endometriosis | 3.1 | 1.9 | 0.63 |
| Eosinophilic Esophagitis | 0.3 | 0.3 | 0 |
| Epilepsy | 3.1 | 1.4 | 1.21 |
| erectile dysfunction | 1.4 | 1.4 | |
| Fibromyalgia | 3.1 | 1.6 | 0.94 |
| Functional constipation / chronic idiopathic constipation | 3.7 | 2.9 | 0.28 |
| gallstone disease (gsd) | 3 | 0.8 | 2.75 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 1.3 | 0.3 | 3.33 |
| Generalized anxiety disorder | 2.7 | 1.1 | 1.45 |
| giant cell arteritis | 0.2 | -0.2 | |
| Glioblastoma | 0.3 | -0.3 | |
| Gout | 0.9 | 0.5 | 0.8 |
| Graves' disease | 1.3 | 2.7 | -1.08 |
| Gulf War Syndrome | 0.9 | 0.2 | 3.5 |
| Halitosis | 1.5 | 0.3 | 4 |
| Hashimoto's thyroiditis | 2.6 | 0.5 | 4.2 |
| Heart Failure | 3.5 | 1 | 2.5 |
| hemorrhagic stroke | 1.3 | 1.3 | |
| Hidradenitis Suppurativa | 0.9 | 0.9 | |
| High Histamine/low DAO | 1.8 | 0.3 | 5 |
| hypercholesterolemia (High Cholesterol) | 1 | 1 | |
| hyperglycemia | 1.6 | 0.9 | 0.78 |
| Hyperlipidemia (High Blood Fats) | 0.3 | 0.3 | 0 |
| hypersomnia | 0.4 | -0.4 | |
| hypertension (High Blood Pressure | 3.7 | 2.4 | 0.54 |
| Hypothyroidism | 0.7 | -0.7 | |
| Hypoxia | 3.1 | 3.1 | |
| IgA nephropathy (IgAN) | 1.9 | 1.4 | 0.36 |
| Inflammatory Bowel Disease | 6.1 | 3.9 | 0.56 |
| Insomnia | 2.1 | 1.6 | 0.31 |
| Intelligence | 1.5 | 0.2 | 6.5 |
| Intracranial aneurysms | 1.4 | 0.6 | 1.33 |
| Irritable Bowel Syndrome | 4.6 | 3.2 | 0.44 |
| ischemic stroke | 1.9 | 1.4 | 0.36 |
| Liver Cirrhosis | 5.8 | 3.3 | 0.76 |
| Long COVID | 4.5 | 3.7 | 0.22 |
| Low bone mineral density | 0.8 | -0.8 | |
| Lung Cancer | 0.6 | 1 | -0.67 |
| Lymphoma | 0.6 | 0.6 | |
| Mast Cell Issues / mastitis | 1.5 | 0.6 | 1.5 |
| ME/CFS with IBS | 0.9 | 1.1 | -0.22 |
| ME/CFS without IBS | 1.1 | 1.2 | -0.09 |
| membranous nephropathy | 0.3 | 0.3 | |
| Menopause | 0.4 | 0.5 | -0.25 |
| Metabolic Syndrome | 5.6 | 4.3 | 0.3 |
| Mood Disorders | 6.6 | 4.9 | 0.35 |
| multiple chemical sensitivity [MCS] | 0.8 | 0.1 | 7 |
| Multiple Sclerosis | 5.2 | 3.8 | 0.37 |
| Multiple system atrophy (MSA) | 0.5 | 0.4 | 0.25 |
| myasthenia gravis | 0.9 | 0.7 | 0.29 |
| neuropathic pain | 0.3 | 1.5 | -4 |
| Neuropathy (all types) | 0.7 | 1.7 | -1.43 |
| neuropsychiatric disorders (PANDAS, PANS) | 1.1 | 1.1 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 5 | 1.9 | 1.63 |
| NonCeliac Gluten Sensitivity | 1 | 0.3 | 2.33 |
| Obesity | 6 | 5.7 | 0.05 |
| obsessive-compulsive disorder | 3 | 2.3 | 0.3 |
| Osteoarthritis | 2.2 | 0.9 | 1.44 |
| Osteoporosis | 2.2 | 1.3 | 0.69 |
| pancreatic cancer | 1.2 | 0.3 | 3 |
| Parkinson's Disease | 5.3 | 4.4 | 0.2 |
| Polycystic ovary syndrome | 4.6 | 2.2 | 1.09 |
| Postural orthostatic tachycardia syndrome | 0.2 | 0.3 | -0.5 |
| Premenstrual dysphoric disorder | 0.4 | 0.4 | 0 |
| primary biliary cholangitis | 0.9 | 1.3 | -0.44 |
| Primary sclerosing cholangitis | 1.9 | 1.5 | 0.27 |
| Psoriasis | 1.9 | 1.9 | 0 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 5.3 | 3.1 | 0.71 |
| Rosacea | 0.5 | 0.7 | -0.4 |
| Schizophrenia | 3.9 | 2.2 | 0.77 |
| scoliosis | 0.8 | 0.3 | 1.67 |
| Sjögren syndrome | 2 | 1.7 | 0.18 |
| Sleep Apnea | 1.6 | 1.8 | -0.13 |
| Slow gastric motility / Gastroparesis | 1.1 | 1.1 | |
| Small Intestinal Bacterial Overgrowth (SIBO) | 1.8 | 1.8 | |
| Stress / posttraumatic stress disorder | 2.8 | 2.1 | 0.33 |
| Systemic Lupus Erythematosus | 3.3 | 1.3 | 1.54 |
| Tic Disorder | 1 | 1.1 | -0.1 |
| Tourette syndrome | 0.9 | 0.3 | 2 |
| Type 1 Diabetes | 2.6 | 1.8 | 0.44 |
| Type 2 Diabetes | 6.2 | 4.5 | 0.38 |
| Ulcerative colitis | 4.9 | 3.4 | 0.44 |
| Unhealthy Ageing | 3.7 | 1.6 | 1.31 |
| Vitiligo | 1.5 | 1.2 | 0.25 |
