AI Engines For more Details: Perplexity Kagi Labs You
Allergic Reactions: Diphenhydramine hydrochloride is effective in relieving symptoms of allergic reactions, including itching, hives, and rash. It works by blocking the action of histamine, a substance produced by the body during an allergic response, thereby reducing the allergic symptoms.
Nasal Congestion: Diphenhydramine can help alleviate nasal congestion associated with allergies or the common cold by reducing swelling in the nasal passages and decreasing mucus production.
Sleep Disorders: Due to its sedative effects, diphenhydramine hydrochloride is often used to treat insomnia and other sleep disorders. It can help individuals fall asleep faster and improve the quality and duration of sleep.
Motion Sickness: Diphenhydramine is sometimes used to prevent and treat motion sickness. It can help alleviate nausea, vomiting, and dizziness associated with motion sickness when taken before traveling.
Parkinson's Disease: Diphenhydramine hydrochloride may be used as an adjunctive treatment in Parkinson's disease to help alleviate symptoms such as tremors and muscle rigidity. It has anticholinergic properties that can help reduce the excessive activity of acetylcholine, a neurotransmitter involved in motor control.
Pruritus: Diphenhydramine is also used to relieve itching associated with various skin conditions, such as eczema, dermatitis, and insect bites. It helps alleviate itching by blocking histamine receptors in the skin and reducing the sensation of itch.
Anaphylaxis: In emergency situations, diphenhydramine hydrochloride may be administered as part of the treatment for anaphylaxis, a severe and potentially life-threatening allergic reaction. It can help reduce symptoms such as swelling, itching, and hives, although it is not a substitute for epinephrine, which is the first-line treatment for anaphylaxis.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Akkermansia muciniphila | Reduces |
| species | Bacteroides uniformis | Reduces |
| species | Escherichia coli | Reduces |
| species | Lacticaseibacillus paracasei | Reduces |
| species | Parabacteroides distasonis | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.9 | 0.9 | |
| Acne | 0.3 | 0.6 | -1 |
| ADHD | 2.2 | 2.2 | |
| Age-Related Macular Degeneration and Glaucoma | 0.4 | -0.4 | |
| Allergic Rhinitis (Hay Fever) | 2.2 | 0.8 | 1.75 |
| Allergies | 3.2 | 1.6 | 1 |
| Allergy to milk products | 0.9 | 1.3 | -0.44 |
| Alopecia (Hair Loss) | 0.6 | 0.6 | |
| Alzheimer's disease | 4.2 | 3.4 | 0.24 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 2.3 | 0.7 | 2.29 |
| Ankylosing spondylitis | 2.6 | 0.9 | 1.89 |
| Anorexia Nervosa | 0.7 | 1.5 | -1.14 |
| Antiphospholipid syndrome (APS) | 1.2 | 0.3 | 3 |
| Asthma | 1.8 | 1.1 | 0.64 |
| Atherosclerosis | 1.2 | 1.3 | -0.08 |
| Atrial fibrillation | 1.6 | 2.7 | -0.69 |
| Autism | 5.1 | 5.9 | -0.16 |
| Autoimmune Disease | 0.9 | 0.9 | |
| Barrett esophagus cancer | 0.3 | 0.3 | 0 |
| benign prostatic hyperplasia | 0.6 | 0.3 | 1 |
| Biofilm | 1.2 | 1.2 | |
| Bipolar Disorder | 1.6 | 1.6 | |
| Brain Trauma | 0.3 | 0.3 | 0 |
| Breast Cancer | 0.5 | 0.5 | |
| Cancer (General) | 0.6 | 0.2 | 2 |
| Carcinoma | 2.7 | 1 | 1.7 |
| Celiac Disease | 2 | 1.5 | 0.33 |
| Cerebral Palsy | 0.8 | 0.3 | 1.67 |
| Chronic Fatigue Syndrome | 2.1 | 3.1 | -0.48 |
| Chronic Kidney Disease | 2.4 | 1.7 | 0.41 |
| Chronic Lyme | 0.1 | 0.3 | -2 |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.9 | 0.6 | 0.5 |
| Chronic Urticaria (Hives) | 1.2 | 1.1 | 0.09 |
| Coagulation / Micro clot triggering bacteria | 1.6 | 0.3 | 4.33 |
| Cognitive Function | 1 | 0.6 | 0.67 |
| Colorectal Cancer | 6.5 | 1.3 | 4 |
| Constipation | 1.7 | 1.7 | |
| Coronary artery disease | 1.8 | 1.6 | 0.13 |
| COVID-19 | 4.9 | 5 | -0.02 |
| Crohn's Disease | 5.6 | 2.9 | 0.93 |
| Cushing's Syndrome (hypercortisolism) | 0.9 | -0.9 | |
| cystic fibrosis | 0.9 | 0.3 | 2 |
| d-lactic acidosis (one form of brain fog) | 0.3 | 0.3 | |
| deep vein thrombosis | 1.6 | 0.6 | 1.67 |
| Denture Wearers Oral Shifts | 0.5 | 0.5 | |
| Depression | 5.9 | 4.2 | 0.4 |
| Dermatomyositis | 0.3 | 0.3 | |
| Eczema | 1.5 | 0.6 | 1.5 |
| Endometriosis | 1.9 | 0.6 | 2.17 |
| Eosinophilic Esophagitis | 0.3 | 0.3 | 0 |
| Epilepsy | 2.3 | 1.6 | 0.44 |
| erectile dysfunction | 1.5 | 1.5 | |
| Fibromyalgia | 0.7 | 1.7 | -1.43 |
| Functional constipation / chronic idiopathic constipation | 3.1 | 2.1 | 0.48 |
| gallstone disease (gsd) | 2 | 0.5 | 3 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 1.4 | 0.3 | 3.67 |
| Generalized anxiety disorder | 2.3 | 0.8 | 1.87 |
| Glioblastoma | 0.3 | -0.3 | |
| Gout | 1.4 | 0.2 | 6 |
| Graves' disease | 0.7 | 0.6 | 0.17 |
| Gulf War Syndrome | 0.3 | 1.5 | -4 |
| Halitosis | 1.1 | 0.3 | 2.67 |
| Hashimoto's thyroiditis | 1.7 | 1.3 | 0.31 |
| Heart Failure | 2.7 | 1.5 | 0.8 |
| hemorrhagic stroke | 0.7 | 0.7 | |
| Hidradenitis Suppurativa | 1.2 | 1.2 | |
| High Histamine/low DAO | 0.3 | 0.3 | |
| hypercholesterolemia (High Cholesterol) | 0.6 | 0.4 | 0.5 |
| hyperglycemia | 1.5 | 1.3 | 0.15 |
| Hyperlipidemia (High Blood Fats) | 0.5 | 0.5 | |
| hypersomnia | 0.3 | -0.3 | |
| hypertension (High Blood Pressure | 3 | 2.3 | 0.3 |
| Hypothyroidism | 1.1 | 1.1 | |
| Hypoxia | 1.8 | 0.4 | 3.5 |
| IgA nephropathy (IgAN) | 1.3 | 2 | -0.54 |
| Inflammatory Bowel Disease | 4.5 | 4.4 | 0.02 |
| Insomnia | 0.6 | 1.4 | -1.33 |
| Intelligence | 1.2 | 0.4 | 2 |
| Intracranial aneurysms | 1 | 1 | |
| Irritable Bowel Syndrome | 4.1 | 2.7 | 0.52 |
| ischemic stroke | 1.5 | 1.2 | 0.25 |
| Liver Cirrhosis | 3.5 | 2.6 | 0.35 |
| Long COVID | 4.2 | 2.7 | 0.56 |
| Lung Cancer | 0.9 | 0.4 | 1.25 |
| Lymphoma | 0.9 | 0.9 | |
| Mast Cell Issues / mastitis | 1.1 | 1.1 | |
| ME/CFS with IBS | 0.3 | 0.3 | 0 |
| ME/CFS without IBS | 0.6 | 0.9 | -0.5 |
| membranous nephropathy | 0.3 | 0.3 | |
| Menopause | 0.3 | 0.2 | 0.5 |
| Metabolic Syndrome | 3.7 | 3.9 | -0.05 |
| Mood Disorders | 5.4 | 3.6 | 0.5 |
| multiple chemical sensitivity [MCS] | 0.5 | 0.5 | |
| Multiple Sclerosis | 3.3 | 3 | 0.1 |
| Multiple system atrophy (MSA) | 0.7 | 0.7 | |
| myasthenia gravis | 0.9 | 0.9 | |
| neuropathic pain | 1.2 | -1.2 | |
| Neuropathy (all types) | 0.5 | 1.6 | -2.2 |
| neuropsychiatric disorders (PANDAS, PANS) | 0.8 | 0.8 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 2.4 | 1.8 | 0.33 |
| NonCeliac Gluten Sensitivity | 0.7 | 0.3 | 1.33 |
| Obesity | 6.2 | 3.8 | 0.63 |
| obsessive-compulsive disorder | 3.5 | 2.9 | 0.21 |
| Osteoarthritis | 2.1 | 0.8 | 1.63 |
| Osteoporosis | 0.9 | 1 | -0.11 |
| pancreatic cancer | 1.7 | 0.6 | 1.83 |
| Parkinson's Disease | 4.6 | 3.5 | 0.31 |
| Polycystic ovary syndrome | 4.1 | 1.3 | 2.15 |
| Premenstrual dysphoric disorder | 0.4 | -0.4 | |
| primary biliary cholangitis | 0.3 | 1.2 | -3 |
| Primary sclerosing cholangitis | 1.4 | 1.4 | 0 |
| Psoriasis | 1.1 | 2.8 | -1.55 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 3 | 1.9 | 0.58 |
| Rosacea | 0.6 | 0.6 | |
| Schizophrenia | 3.4 | 0.9 | 2.78 |
| scoliosis | 0.3 | 0.3 | 0 |
| Sjögren syndrome | 2 | 1.6 | 0.25 |
| Sleep Apnea | 0.3 | 0.3 | 0 |
| Slow gastric motility / Gastroparesis | 0.6 | 0.6 | |
| Small Intestinal Bacterial Overgrowth (SIBO) | 1.1 | 1.1 | |
| Stress / posttraumatic stress disorder | 1.5 | 1.1 | 0.36 |
| Systemic Lupus Erythematosus | 3.2 | 0.3 | 9.67 |
| Tic Disorder | 1.1 | 0.4 | 1.75 |
| Tourette syndrome | 0.5 | 0.3 | 0.67 |
| Type 1 Diabetes | 3.3 | 1.1 | 2 |
| Type 2 Diabetes | 4.8 | 4.3 | 0.12 |
| Ulcerative colitis | 3 | 4.5 | -0.5 |
| Unhealthy Ageing | 3.3 | 1.6 | 1.06 |
| Vitiligo | 1.3 | 0.6 | 1.17 |
