AI Engines For more Details: Perplexity Kagi Labs You
Increased LDL Cholesterol: Hydrogenation, the process used to solidify liquid vegetable oils, leads to the formation of trans fats. Trans fats are known to raise levels of LDL (low-density lipoprotein) cholesterol, commonly referred to as "bad" cholesterol, in the bloodstream. Elevated LDL cholesterol is a risk factor for cardiovascular diseases such as coronary artery disease and stroke.
Decreased HDL Cholesterol: In addition to raising LDL cholesterol, trans fats have been shown to decrease levels of HDL (high-density lipoprotein) cholesterol, often referred to as "good" cholesterol. HDL cholesterol helps remove LDL cholesterol from the bloodstream, so lower levels of HDL can further contribute to cardiovascular risk.
Increased Risk of Heart Disease: Consumption of trans fats from hydrogenated oils has been linked to an increased risk of heart disease, including heart attacks and atherosclerosis (hardening of the arteries). The combination of raising LDL cholesterol and lowering HDL cholesterol contributes to the development of cardiovascular complications.
Inflammation: Trans fats have been associated with increased inflammation in the body, which is a contributing factor to various chronic diseases, including cardiovascular disease, diabetes, and certain cancers. Chronic inflammation can damage blood vessels and promote the development of atherosclerosis.
Insulin Resistance and Diabetes Risk: Some studies suggest that high consumption of trans fats may contribute to insulin resistance, a condition in which cells become less responsive to insulin. Insulin resistance is a precursor to type 2 diabetes and can lead to elevated blood sugar levels over time.
Obesity and Weight Gain: Although not directly caused by hydrogenated palm oil itself, foods high in trans fats, including those containing hydrogenated oils, are often energy-dense and nutrient-poor. Regular consumption of these foods may contribute to weight gain and obesity, which are risk factors for numerous chronic health conditions.
Digestive Issues: While not as widely studied as the cardiovascular effects, some individuals may experience digestive discomfort or issues such as bloating, gas, or diarrhea after consuming foods containing hydrogenated palm oil. These symptoms can vary depending on individual tolerance levels and overall dietary habits.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Akkermansia muciniphila | Increases |
| species | Blautia hansenii | Increases |
| species | Blautia wexlerae | Increases |
| species | Lactobacillus acidophilus | Increases |
| species | Lactobacillus crispatus | Increases |
| species | Lactobacillus gasseri | Increases |
| species | Lactobacillus helveticus | Increases |
| species | Lactobacillus jensenii | Increases |
| species | Lactobacillus johnsonii | Increases |
| species | Lactobacillus kefiranofaciens | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.2 | 0.6 | -2 |
| Acne | 2.4 | 0.8 | 2 |
| ADHD | 4.8 | 2.9 | 0.66 |
| Age-Related Macular Degeneration and Glaucoma | 1 | 0.8 | 0.25 |
| Allergic Rhinitis (Hay Fever) | 2.2 | 3.4 | -0.55 |
| Allergies | 8.1 | 5.7 | 0.42 |
| Allergy to milk products | 0.5 | 4.5 | -8 |
| Alopecia (Hair Loss) | 0.8 | 2.2 | -1.75 |
| Alzheimer's disease | 11 | 7.2 | 0.53 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 1.3 | 5.8 | -3.46 |
| Ankylosing spondylitis | 3.8 | 5.3 | -0.39 |
| Anorexia Nervosa | 5.2 | 2.1 | 1.48 |
| Antiphospholipid syndrome (APS) | 0.5 | 0.5 | 0 |
| Asthma | 5.4 | 4.6 | 0.17 |
| Atherosclerosis | 3.7 | 2.3 | 0.61 |
| Atrial fibrillation | 3.8 | 3.8 | 0 |
| Autism | 10.3 | 9.4 | 0.1 |
| Autoimmune Disease | 3 | 0.7 | 3.29 |
| Barrett esophagus cancer | 0.6 | 0.6 | |
| benign prostatic hyperplasia | 1.4 | 1.4 | |
| Biofilm | 0.2 | -0.2 | |
| Bipolar Disorder | 4.2 | 2.6 | 0.62 |
| Brain Trauma | 2.9 | 0.9 | 2.22 |
| Breast Cancer | 0.3 | 0.6 | -1 |
| Cancer (General) | 0.6 | 0.6 | 0 |
| Carcinoma | 2.8 | 3.9 | -0.39 |
| Celiac Disease | 6.8 | 3.4 | 1 |
| Cerebral Palsy | 2.7 | 1.4 | 0.93 |
| Chronic Fatigue Syndrome | 4.5 | 2.5 | 0.8 |
| Chronic Kidney Disease | 4.6 | 1.9 | 1.42 |
| Chronic Lyme | 0.4 | 0.4 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 3.4 | 3.1 | 0.1 |
| Chronic Urticaria (Hives) | 3.7 | 3.7 | |
| Coagulation / Micro clot triggering bacteria | 3.4 | 0.3 | 10.33 |
| Cognitive Function | 2.1 | 3.8 | -0.81 |
| Colorectal Cancer | 3.8 | 6.8 | -0.79 |
| Constipation | 2.2 | 1.6 | 0.38 |
| Coronary artery disease | 5.5 | 2.5 | 1.2 |
| COVID-19 | 12 | 5.7 | 1.11 |
| Crohn's Disease | 10 | 8.9 | 0.12 |
| Cushing's Syndrome (hypercortisolism) | 0 | 0 | |
| cystic fibrosis | 2.6 | 0.2 | 12 |
| d-lactic acidosis (one form of brain fog) | 1 | -1 | |
| deep vein thrombosis | 2.6 | 1.6 | 0.63 |
| Denture Wearers Oral Shifts | 0.6 | 0.3 | 1 |
| Depression | 11.7 | 10.7 | 0.09 |
| Dermatomyositis | 0.3 | 1 | -2.33 |
| Eczema | 0.2 | 0.8 | -3 |
| Endometriosis | 4 | 3.7 | 0.08 |
| Eosinophilic Esophagitis | 0.8 | 0.6 | 0.33 |
| Epilepsy | 5.3 | 4.8 | 0.1 |
| erectile dysfunction | 1.7 | 1 | 0.7 |
| Fibromyalgia | 3.6 | 3.7 | -0.03 |
| Functional constipation / chronic idiopathic constipation | 6.3 | 5 | 0.26 |
| gallstone disease (gsd) | 2.7 | 3 | -0.11 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 3.2 | 1.9 | 0.68 |
| Generalized anxiety disorder | 2 | 4.2 | -1.1 |
| giant cell arteritis | 0.3 | -0.3 | |
| Glioblastoma | 2.5 | 2.5 | |
| Gout | 2.5 | 3.1 | -0.24 |
| Graves' disease | 5.3 | 2.2 | 1.41 |
| Gulf War Syndrome | 2.1 | 1.2 | 0.75 |
| Halitosis | 1.5 | 1.4 | 0.07 |
| Hashimoto's thyroiditis | 4.2 | 4.4 | -0.05 |
| Heart Failure | 5.7 | 3.6 | 0.58 |
| hemorrhagic stroke | 0.6 | 1.5 | -1.5 |
| Hemorrhoidal disease, Hemorrhoids, Piles | 0.3 | -0.3 | |
| Hidradenitis Suppurativa | 0.6 | 0.7 | -0.17 |
| High Histamine/low DAO | 1.2 | 1 | 0.2 |
| hypercholesterolemia (High Cholesterol) | 1.2 | 0.9 | 0.33 |
| hyperglycemia | 2.8 | 1.8 | 0.56 |
| Hyperlipidemia (High Blood Fats) | 3 | 1.4 | 1.14 |
| hypersomnia | 1 | 0.9 | 0.11 |
| hypertension (High Blood Pressure | 7.5 | 7.5 | 0 |
| Hypothyroidism | 4.1 | 3.8 | 0.08 |
| Hypoxia | 1.2 | 1.8 | -0.5 |
| IgA nephropathy (IgAN) | 5.2 | 2.3 | 1.26 |
| Inflammatory Bowel Disease | 9.9 | 5.2 | 0.9 |
| Insomnia | 6.2 | 5.5 | 0.13 |
| Intelligence | 1.9 | 2.5 | -0.32 |
| Intracranial aneurysms | 1.7 | 2.7 | -0.59 |
| Irritable Bowel Syndrome | 7.7 | 9.6 | -0.25 |
| ischemic stroke | 4.8 | 3.3 | 0.45 |
| Juvenile idiopathic arthritis | 0.5 | 0.5 | |
| Liver Cirrhosis | 6.9 | 7.3 | -0.06 |
| Long COVID | 11.3 | 7.2 | 0.57 |
| Low bone mineral density | 2.2 | 0.5 | 3.4 |
| Lung Cancer | 3 | 0.2 | 14 |
| Lymphoma | 0.6 | 0.6 | |
| Mast Cell Issues / mastitis | 2.9 | 0.5 | 4.8 |
| ME/CFS with IBS | 1.2 | 1.2 | |
| ME/CFS without IBS | 0.3 | 0.3 | 0 |
| membranous nephropathy | 0.1 | 0.6 | -5 |
| Menopause | 2.3 | 0.9 | 1.56 |
| Metabolic Syndrome | 11.1 | 8.9 | 0.25 |
| Mood Disorders | 10.1 | 11.7 | -0.16 |
| multiple chemical sensitivity [MCS] | 0.6 | 1.2 | -1 |
| Multiple Sclerosis | 9.1 | 5.8 | 0.57 |
| Multiple system atrophy (MSA) | 0.8 | 2.2 | -1.75 |
| myasthenia gravis | 1 | 1.2 | -0.2 |
| neuropathic pain | 2 | 2 | |
| Neuropathy (all types) | 1.3 | 2.4 | -0.85 |
| neuropsychiatric disorders (PANDAS, PANS) | 1.6 | 1.6 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 10.1 | 6.3 | 0.6 |
| NonCeliac Gluten Sensitivity | 1.6 | 1.7 | -0.06 |
| Obesity | 13.4 | 13 | 0.03 |
| obsessive-compulsive disorder | 6.3 | 2.2 | 1.86 |
| Osteoarthritis | 2 | 2 | 0 |
| Osteoporosis | 5.5 | 2.5 | 1.2 |
| pancreatic cancer | 1 | 0.6 | 0.67 |
| Parkinson's Disease | 11.5 | 9.3 | 0.24 |
| Peanut Allergy | 0.4 | 0.4 | |
| Polycystic ovary syndrome | 6 | 5.4 | 0.11 |
| Postural orthostatic tachycardia syndrome | 0.3 | 0.3 | 0 |
| Premenstrual dysphoric disorder | 0.3 | 0.8 | -1.67 |
| primary biliary cholangitis | 1.9 | 1.9 | 0 |
| Primary sclerosing cholangitis | 3.3 | 0.6 | 4.5 |
| Psoriasis | 5.3 | 3.1 | 0.71 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 7.3 | 8.4 | -0.15 |
| Rosacea | 3.2 | 0.3 | 9.67 |
| Schizophrenia | 7.1 | 8.2 | -0.15 |
| scoliosis | 0.9 | 1.3 | -0.44 |
| sensorineural hearing loss | 0.4 | 0.4 | |
| Sjögren syndrome | 3.6 | 3.6 | 0 |
| Sleep Apnea | 2.9 | 3.8 | -0.31 |
| Slow gastric motility / Gastroparesis | 1.2 | 0.9 | 0.33 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 1.1 | 3 | -1.73 |
| Stress / posttraumatic stress disorder | 3.6 | 3.4 | 0.06 |
| Systemic Lupus Erythematosus | 5.5 | 3.9 | 0.41 |
| Tic Disorder | 2.5 | 2 | 0.25 |
| Tourette syndrome | 1.3 | 0.9 | 0.44 |
| Type 1 Diabetes | 4.8 | 5.2 | -0.08 |
| Type 2 Diabetes | 9.3 | 9.2 | 0.01 |
| Ulcerative colitis | 10.3 | 7.1 | 0.45 |
| Unhealthy Ageing | 4.1 | 1.3 | 2.15 |
| Vitiligo | 1.5 | 0.8 | 0.88 |
