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Mental Health: Lactobacillus helveticus has been studied for its potential effects on mental health and mood regulation. Some research suggests that supplementation with L. helveticus may have anxiolytic (anxiety-reducing) and antidepressant effects, potentially by modulating neurotransmitter levels, reducing inflammation, and promoting gut-brain communication via the gut microbiota-brain axis.
Blood Pressure Regulation: There is evidence to suggest that certain strains of Lactobacillus helveticus may have antihypertensive effects, meaning they can help lower blood pressure. These effects may be attributed to the production of bioactive peptides, such as ACE-inhibitory peptides, which can help regulate blood pressure by inhibiting the activity of angiotensin-converting enzyme (ACE).
Immune Function: Lactobacillus helveticus has immunomodulatory properties and may help enhance immune function. It can stimulate the production of certain immune cells and cytokines, promoting a balanced immune response and reducing the risk of infections and inflammatory conditions.
Digestive Health: Probiotics containing Lactobacillus helveticus may contribute to digestive health by promoting a balanced gut microbiota, aiding in the breakdown of food, and producing beneficial metabolites such as short-chain fatty acids. They may help alleviate symptoms of digestive disorders such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diarrhea.
Cholesterol Metabolism: Some research suggests that supplementation with Lactobacillus helveticus may help improve lipid profiles by lowering total cholesterol and LDL cholesterol levels and increasing HDL cholesterol levels. These effects may be mediated by the metabolism of bile acids and the production of bioactive compounds that inhibit cholesterol absorption.
Bone Health: There is emerging evidence to suggest that Lactobacillus helveticus may have beneficial effects on bone health by promoting calcium absorption, reducing bone loss, and increasing bone mineral density. These effects may be mediated by the production of enzymes that enhance mineral bioavailability and the regulation of inflammatory pathways involved in bone remodeling.
Rank | Probiotic | Impact |
---|---|---|
genus | Bacillus | Reduces |
genus | Bifidobacterium | Increases |
species | Akkermansia muciniphila | Reduces |
species | Bacillus aeolius | Reduces |
species | Bacillus horti | Reduces |
species | Bacillus infernus | Reduces |
species | Bacillus pumilus | Reduces |
species | Bacillus thermotolerans | Reduces |
species | Bacillus thuringiensis | Reduces |
species | Bacteroides uniformis | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Taxonomy | Rank | Effect | Citations | Notation |
---|---|---|---|---|
[Clostridium] scindens | species | Decreases | π Source Study | |
[Flavobacterium] lutescens | species | Decreases | πΆ Source Study | |
[Lactobacillus] rogosae | species | Increases | πΆ Source Study | |
[Lactobacillus] rogosae | species | Increases | πΆ Source Study | |
[Propionibacterium] humerusii | Species | Decreases | πΆ Source Study | |
Acetatifactor | genus | Decreases | π Source Study | |
Acetatifactor muris | species | Decreases | πΆ Source Study | |
Acidipropionibacterium | genus | Decreases | π Source Study | |
Acidipropionibacterium acidipropionici | species | Decreases | π Source Study | |
Acidipropionibacterium acidipropionici ATCC 4875 | strain | Decreases | πΆ Source Study | |
Acidipropionibacterium jensenii | species | Decreases | πΆ Source Study | |
Acidipropionibacterium microaerophilum | species | Decreases | πΆ Source Study | |
Acidipropionibacterium thoenii | species | Decreases | πΆ Source Study | |
Acidipropionibacterium virtanenii | species | Decreases | πΆ Source Study | |
Acutalibacter | genus | Decreases | πͺ Source Study |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Abdominal Aortic Aneurysm | 0.2 | 0.2 | |
Acne | 2.2 | 0.3 | 6.33 |
Addison's Disease (hypocortisolism) | 0.5 | 0.5 | |
ADHD | 1.7 | 1.7 | 0 |
Age-Related Macular Degeneration and Glaucoma | 1.1 | -1.1 | |
Allergic Rhinitis (Hay Fever) | 4 | 3.3 | 0.21 |
Allergies | 7.5 | 4.4 | 0.7 |
Allergy to milk products | 3.2 | 1.5 | 1.13 |
Alopecia (Hair Loss) | 0.8 | 0.8 | |
Alzheimer's disease | 5.4 | 5.5 | -0.02 |
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