AI Engines For more Details: Perplexity Kagi Labs You
Cholesterol Reduction: Beta-sitosterol is known to inhibit the absorption of cholesterol in the intestine, leading to a reduction in low-density lipoprotein (LDL) cholesterol levels in the blood. LDL cholesterol is often referred to as "bad" cholesterol because high levels of LDL cholesterol are associated with an increased risk of cardiovascular diseases such as coronary artery disease, heart attack, and stroke. By lowering LDL cholesterol levels, beta-sitosterol may help reduce the risk of cardiovascular events.
Triglyceride Reduction: In addition to lowering LDL cholesterol, beta-sitosterol may also have modest effects on reducing triglyceride levels in the blood. Elevated triglyceride levels are another risk factor for cardiovascular disease, and lowering triglyceride levels may contribute to overall cardiovascular health.
Anti-Inflammatory Properties: Beta-sitosterol exhibits anti-inflammatory properties, which may benefit individuals with inflammatory conditions such as arthritis, inflammatory bowel disease (IBD), or cardiovascular disease. By reducing inflammation in the body, beta-sitosterol may help mitigate the progression of these conditions and improve overall health.
Immune Modulation: Some research suggests that beta-sitosterol may modulate the immune system and enhance immune function, potentially reducing the risk of infections and supporting overall immune health.
Prostate Health: Beta-sitosterol has been studied for its potential benefits in promoting prostate health and alleviating symptoms of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland that can cause urinary symptoms such as frequent urination, urgency, and incomplete bladder emptying. Some studies suggest that beta-sitosterol may help improve urinary flow rate and reduce BPH-related symptoms.
Antioxidant Activity: Beta-sitosterol exhibits antioxidant activity, which may help protect against oxidative stress and damage caused by free radicals. Oxidative stress is implicated in the development of various chronic diseases, including cardiovascular disease, cancer, and neurodegenerative disorders. By scavenging free radicals and neutralizing oxidative stress, beta-sitosterol may contribute to overall health and disease prevention.
Blood Sugar Regulation: Some research suggests that beta-sitosterol may have beneficial effects on blood sugar regulation and insulin sensitivity, which could be particularly relevant for individuals with diabetes or metabolic syndrome. By improving insulin sensitivity and glucose metabolism, beta-sitosterol may help maintain stable blood sugar levels and reduce the risk of diabetes-related complications.
| Rank | Probiotic | Impact |
|---|---|---|
| genus | Bifidobacterium | Increases |
| genus | Pediococcus | Increases |
| species | Lactobacillus acidophilus | Reduces |
| species | Lactobacillus crispatus | Reduces |
| species | Lactobacillus gasseri | Reduces |
| species | Lactobacillus helveticus | Reduces |
| species | Lactobacillus jensenii | Reduces |
| species | Lactobacillus johnsonii | Reduces |
| species | Lactobacillus kefiranofaciens | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.6 | 0.6 | 0 |
| Acne | 1.9 | 1.9 | 0 |
| ADHD | 2.4 | 6 | -1.5 |
| Age-Related Macular Degeneration and Glaucoma | 0.6 | 0.5 | 0.2 |
| Allergic Rhinitis (Hay Fever) | 1.4 | 2 | -0.43 |
| Allergies | 6 | 3.6 | 0.67 |
| Allergy to milk products | 3.9 | 1.1 | 2.55 |
| Alopecia (Hair Loss) | 2.6 | 2.6 | |
| Alzheimer's disease | 9 | 6.9 | 0.3 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 3.5 | 2.1 | 0.67 |
| Ankylosing spondylitis | 4.8 | 2.4 | 1 |
| Anorexia Nervosa | 1.3 | 4.6 | -2.54 |
| Antiphospholipid syndrome (APS) | 0.6 | -0.6 | |
| Asthma | 4 | 3.8 | 0.05 |
| Atherosclerosis | 0.7 | 2.8 | -3 |
| Atrial fibrillation | 4.3 | 2.9 | 0.48 |
| Autism | 8.8 | 7.3 | 0.21 |
| Autoimmune Disease | 1.2 | 1.7 | -0.42 |
| Barrett esophagus cancer | 0.5 | 0.5 | |
| benign prostatic hyperplasia | 0.3 | -0.3 | |
| Biofilm | 0.2 | -0.2 | |
| Bipolar Disorder | 2.9 | 2.3 | 0.26 |
| Brain Trauma | 3 | 1.6 | 0.88 |
| Breast Cancer | 0.4 | 0.3 | 0.33 |
| Cancer (General) | 0.7 | 1.2 | -0.71 |
| Carcinoma | 3 | 3 | 0 |
| Celiac Disease | 3.2 | 4.8 | -0.5 |
| Cerebral Palsy | 0.6 | 2.2 | -2.67 |
| Chronic Fatigue Syndrome | 3.2 | 3.8 | -0.19 |
| Chronic Kidney Disease | 1.9 | 4 | -1.11 |
| Chronic Lyme | 0.3 | -0.3 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 3.3 | 1.9 | 0.74 |
| Chronic Urticaria (Hives) | 0.6 | 1.3 | -1.17 |
| Coagulation / Micro clot triggering bacteria | 0.5 | 2 | -3 |
| Cognitive Function | 4.1 | 3.4 | 0.21 |
| Colorectal Cancer | 6.5 | 3.7 | 0.76 |
| Constipation | 1.9 | 1 | 0.9 |
| Coronary artery disease | 2.3 | 3.2 | -0.39 |
| COVID-19 | 6.9 | 9 | -0.3 |
| Crohn's Disease | 6 | 8.2 | -0.37 |
| cystic fibrosis | 0.6 | 0.9 | -0.5 |
| d-lactic acidosis (one form of brain fog) | 1 | 0.2 | 4 |
| deep vein thrombosis | 1 | 1.3 | -0.3 |
| Denture Wearers Oral Shifts | 0.3 | 0.2 | 0.5 |
| Depression | 8.8 | 10.2 | -0.16 |
| Dermatomyositis | 1.9 | 0.5 | 2.8 |
| Eczema | 2.4 | 2.4 | |
| Endometriosis | 2.7 | 2.8 | -0.04 |
| Eosinophilic Esophagitis | 1 | 1.9 | -0.9 |
| Epilepsy | 4.2 | 3.5 | 0.2 |
| erectile dysfunction | 1.5 | 1.5 | |
| Fibromyalgia | 2.8 | 1.3 | 1.15 |
| Functional constipation / chronic idiopathic constipation | 4.9 | 4.3 | 0.14 |
| gallstone disease (gsd) | 1.8 | 0.6 | 2 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 3.6 | 2.3 | 0.57 |
| Generalized anxiety disorder | 2.2 | 1.4 | 0.57 |
| giant cell arteritis | 0.2 | -0.2 | |
| Glioblastoma | 0.6 | 0.8 | -0.33 |
| Gout | 2.7 | 2.1 | 0.29 |
| Graves' disease | 3.7 | 5.8 | -0.57 |
| Gulf War Syndrome | 3.1 | 2.1 | 0.48 |
| Halitosis | 0.3 | 2.3 | -6.67 |
| Hashimoto's thyroiditis | 4 | 3.7 | 0.08 |
| Heart Failure | 2.2 | 3.4 | -0.55 |
| hemorrhagic stroke | 1.3 | 0.8 | 0.63 |
| Hidradenitis Suppurativa | 0.7 | 1.7 | -1.43 |
| High Histamine/low DAO | 2 | 0.3 | 5.67 |
| hypercholesterolemia (High Cholesterol) | 1.4 | 0.6 | 1.33 |
| hyperglycemia | 1.7 | 0.9 | 0.89 |
| Hyperlipidemia (High Blood Fats) | 1.5 | 2.9 | -0.93 |
| hypersomnia | 2.9 | -2.9 | |
| hypertension (High Blood Pressure | 6.6 | 5.3 | 0.25 |
| Hypothyroidism | 0.8 | 2.9 | -2.62 |
| Hypoxia | 1.7 | 0.8 | 1.13 |
| IgA nephropathy (IgAN) | 2.4 | 2.1 | 0.14 |
| Inflammatory Bowel Disease | 5.1 | 7.2 | -0.41 |
| Insomnia | 4.3 | 2.1 | 1.05 |
| Intelligence | 2.1 | 0.5 | 3.2 |
| Intracranial aneurysms | 1.7 | 1.9 | -0.12 |
| Irritable Bowel Syndrome | 6.4 | 4.7 | 0.36 |
| ischemic stroke | 2.3 | 3.4 | -0.48 |
| Juvenile idiopathic arthritis | 0.5 | 0.7 | -0.4 |
| Liver Cirrhosis | 5.2 | 4.2 | 0.24 |
| Long COVID | 7 | 11.4 | -0.63 |
| Low bone mineral density | 0.5 | 1.2 | -1.4 |
| Lung Cancer | 0.6 | 2.5 | -3.17 |
| Lymphoma | 0 | 0 | |
| Mast Cell Issues / mastitis | 2.1 | 1.1 | 0.91 |
| ME/CFS with IBS | 0.6 | 0 | 0 |
| ME/CFS without IBS | 0.6 | 0.3 | 1 |
| membranous nephropathy | 0.6 | -0.6 | |
| Menopause | 1.2 | -1.2 | |
| Metabolic Syndrome | 9.1 | 8.6 | 0.06 |
| Mood Disorders | 10.4 | 9.5 | 0.09 |
| multiple chemical sensitivity [MCS] | 0.2 | 0.4 | -1 |
| Multiple Sclerosis | 5 | 5 | 0 |
| Multiple system atrophy (MSA) | 1.2 | 0.4 | 2 |
| myasthenia gravis | 0.8 | 0.3 | 1.67 |
| neuropathic pain | 0.6 | 1.4 | -1.33 |
| Neuropathy (all types) | 2.9 | 1.8 | 0.61 |
| neuropsychiatric disorders (PANDAS, PANS) | 0.5 | 1.2 | -1.4 |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 5.8 | 5.6 | 0.04 |
| NonCeliac Gluten Sensitivity | 2 | 2.3 | -0.15 |
| Obesity | 9.7 | 9.4 | 0.03 |
| obsessive-compulsive disorder | 1.6 | 2.7 | -0.69 |
| Osteoarthritis | 2 | 1.1 | 0.82 |
| Osteoporosis | 2.1 | 3.1 | -0.48 |
| pancreatic cancer | 0.5 | 1 | -1 |
| Parkinson's Disease | 8.6 | 9.6 | -0.12 |
| Peanut Allergy | 0.7 | 0.5 | 0.4 |
| Polycystic ovary syndrome | 5.4 | 5.5 | -0.02 |
| Postural orthostatic tachycardia syndrome | 0.9 | 0.3 | 2 |
| Premenstrual dysphoric disorder | 1.2 | 1.9 | -0.58 |
| primary biliary cholangitis | 1.8 | 2.3 | -0.28 |
| Primary sclerosing cholangitis | 1.2 | 2.8 | -1.33 |
| Psoriasis | 2.3 | 2.9 | -0.26 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 7.6 | 7.1 | 0.07 |
| Rosacea | 1.6 | 1.5 | 0.07 |
| Schizophrenia | 8.8 | 4.8 | 0.83 |
| scoliosis | 1.4 | 0.6 | 1.33 |
| sensorineural hearing loss | 0.7 | -0.7 | |
| Sjögren syndrome | 2.5 | 2.5 | 0 |
| Sleep Apnea | 2 | 2.8 | -0.4 |
| Slow gastric motility / Gastroparesis | 1.2 | 0.8 | 0.5 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.9 | 1.1 | -0.22 |
| Stress / posttraumatic stress disorder | 2.2 | 2.8 | -0.27 |
| Systemic Lupus Erythematosus | 3.7 | 5.4 | -0.46 |
| Tic Disorder | 1.6 | 1.4 | 0.14 |
| Tourette syndrome | 0.3 | 0.2 | 0.5 |
| Type 1 Diabetes | 4.5 | 2.1 | 1.14 |
| Type 2 Diabetes | 9 | 7 | 0.29 |
| Ulcerative colitis | 7 | 8.6 | -0.23 |
| Unhealthy Ageing | 2.8 | 2 | 0.4 |
| Vitiligo | 1.2 | 0.9 | 0.33 |
