🍽️ Sucralose {Splenda}

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  1. Weight Management: Sucralose is a zero-calorie sweetener, making it a popular choice for individuals looking to reduce calorie intake and manage their weight. By providing sweetness without adding calories, sucralose can be used as part of a calorie-controlled diet to help control energy balance and support weight loss or weight maintenance goals.

  2. Blood Sugar Control: Sucralose does not significantly affect blood glucose levels or insulin secretion in healthy individuals. It can be a suitable sugar substitute for people with diabetes or those aiming to manage blood sugar levels. However, it's important to note that individual responses to sucralose may vary, and some studies have suggested potential effects on glucose metabolism in certain populations.

  3. Dental Health: Sucralose is non-cariogenic, meaning it does not contribute to tooth decay. Unlike sugar, sucralose does not ferment in the mouth and does not provide a substrate for bacteria that cause dental caries. As a result, sucralose-containing products are less likely to contribute to oral health problems such as cavities and gum disease.

  4. Gastrointestinal Tolerance: Most people tolerate sucralose well, and it does not typically cause gastrointestinal symptoms when consumed in moderation. However, some individuals may experience digestive discomfort, bloating, gas, or diarrhea after consuming foods or beverages containing sucralose, especially when consumed in large amounts or in combination with other artificial sweeteners.

  5. Gut Microbiota: Some studies have suggested that sucralose may alter the composition and activity of the gut microbiota, the community of microorganisms living in the digestive tract. Changes in gut microbiota composition have been linked to various health conditions, including metabolic disorders, inflammatory bowel diseases, and immune dysfunction. However, further research is needed to fully understand the effects of sucralose on gut health and microbiota composition.

  6. Metabolic Effects: There is ongoing debate and research regarding the potential metabolic effects of sucralose consumption. Some studies have suggested that artificial sweeteners, including sucralose, may influence appetite regulation, metabolic hormones, and energy metabolism, potentially affecting body weight and metabolic health. However, the evidence is mixed, and more research is needed to elucidate the long-term metabolic effects of sucralose use.

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Data Contradictions β€” Limits of Certainity

Impacted of Sucralose {Splenda} On Probiotics

Bacteria Impacted by Sucralose {Splenda}

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

Impact of Sucralose {Splenda} on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

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