🍽️ Tudca

Liver Diseases: TUDCA has hepatoprotective properties and is primarily used to treat liver diseases. It has been shown to reduce liver damage, inflammation, and apoptosis (cell death) in conditions such as non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD), cholestasis, and liver fibrosis. TUDCA may help improve liver function and promote liver regeneration by inhibiting ER stress and mitochondrial dysfunction.

Biliary Disorders: TUDCA is used to dissolve gallstones in patients who cannot undergo surgery. It can help dissolve cholesterol gallstones by reducing the secretion of cholesterol into bile and promoting the solubilization of cholesterol crystals. TUDCA may also improve bile flow and reduce bile duct inflammation in conditions such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC).

Endoplasmic Reticulum (ER) Stress: TUDCA is a potent inhibitor of endoplasmic reticulum (ER) stress, which occurs when unfolded or misfolded proteins accumulate in the ER lumen. ER stress is implicated in the pathogenesis of various diseases, including neurodegenerative disorders (e.g., Alzheimer's disease, Parkinson's disease), diabetes, and inflammatory conditions. TUDCA can alleviate ER stress by stabilizing protein folding and reducing the unfolded protein response (UPR), thereby protecting cells from apoptosis and promoting cell survival.

Neurological Disorders: TUDCA has neuroprotective properties and has been investigated for its potential therapeutic effects in neurological disorders. It can cross the blood-brain barrier and exert antioxidant, anti-inflammatory, and anti-apoptotic effects in the central nervous system. TUDCA may help protect neurons, improve synaptic function, and reduce neuroinflammation in conditions such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, and ischemic stroke.

Metabolic Disorders: TUDCA has been studied for its potential benefits in metabolic disorders such as obesity, insulin resistance, and type 2 diabetes. It can improve insulin sensitivity, glucose metabolism, and lipid profile by reducing ER stress, inflammation, and oxidative stress in metabolic tissues such as the liver, adipose tissue, and skeletal muscle. TUDCA may help mitigate metabolic dysfunction and prevent the progression of metabolic syndrome and related complications.

Gastrointestinal Disorders: TUDCA has been investigated for its potential therapeutic effects in gastrointestinal disorders such as inflammatory bowel disease (IBD) and colitis. It can reduce intestinal inflammation, epithelial damage, and mucosal injury by inhibiting inflammatory signaling pathways and promoting mucosal healing. TUDCA may help alleviate symptoms and improve disease outcomes in patients with IBD and other gastrointestinal conditions.