AI Engines For more Details: Perplexity Kagi Labs You
Skin Irritation: Common side effects of nadifloxacin include skin irritation, redness, itching, and burning sensation at the site of application. These effects are usually mild and transient.
Allergic Reactions: Some individuals may experience allergic reactions to nadifloxacin, which can manifest as rash, hives, swelling, or difficulty breathing. Anaphylaxis, a severe allergic reaction, is rare but possible.
Photosensitivity: Nadifloxacin may increase sensitivity to sunlight, leading to sunburn more easily. Patients using this medication should minimize sun exposure and use sunscreen to reduce the risk of sunburn.
Secondary Infections: Topical antibiotics like nadifloxacin can disrupt the balance of normal skin flora, potentially leading to secondary infections such as fungal infections or antibiotic-associated diarrhea caused by Clostridium difficile bacteria.
Rare but Serious Side Effects: In rare cases, nadifloxacin may cause severe adverse reactions such as severe skin reactions (Stevens-Johnson syndrome or toxic epidermal necrolysis) or allergic reactions requiring immediate medical attention.
Bacterial Resistance: Overuse or misuse of nadifloxacin can contribute to the development of antibiotic-resistant bacterial strains, making infections more difficult to treat in the future.
Drug Interactions: Nadifloxacin is a topical medication, so systemic drug interactions are unlikely. However, patients should inform their healthcare provider about all medications, supplements, and herbal products being used to avoid potential interactions.
Pregnancy and Lactation: The safety of nadifloxacin use during pregnancy and lactation has not been established. Pregnant or breastfeeding women should consult with their healthcare provider before using this medication.
| Rank | Probiotic | Impact |
|---|---|---|
| genus | Bifidobacterium | Reduces |
| species | Bacteroides uniformis | Reduces |
| species | Bifidobacterium adolescentis | Reduces |
| species | Bifidobacterium longum | Reduces |
| species | Escherichia coli | Reduces |
| species | Lacticaseibacillus paracasei | Reduces |
| species | Parabacteroides distasonis | Reduces |
| subspecies | Bifidobacterium longum subsp. infantis | Reduces |
| subspecies | Bifidobacterium longum subsp. longum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.9 | 0.9 | |
| Acne | 0.5 | 0.3 | 0.67 |
| ADHD | 5.1 | 0.6 | 7.5 |
| Age-Related Macular Degeneration and Glaucoma | 1.1 | 0.4 | 1.75 |
| Allergic Rhinitis (Hay Fever) | 3.4 | 3 | 0.13 |
| Allergies | 7 | 3.2 | 1.19 |
| Allergy to milk products | 2 | 1.6 | 0.25 |
| Alopecia (Hair Loss) | 1.6 | 1.6 | |
| Alzheimer's disease | 6.9 | 8.3 | -0.2 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 3.2 | 0.9 | 2.56 |
| Ankylosing spondylitis | 4.8 | 1.8 | 1.67 |
| Anorexia Nervosa | 1.6 | 3.2 | -1 |
| Antiphospholipid syndrome (APS) | 2.1 | 0.3 | 6 |
| Asthma | 6.5 | 2.3 | 1.83 |
| Atherosclerosis | 2.7 | 1.9 | 0.42 |
| Atrial fibrillation | 4.1 | 3.1 | 0.32 |
| Autism | 10.8 | 10.8 | 0 |
| Autoimmune Disease | 1.7 | 1 | 0.7 |
| Barrett esophagus cancer | 0.6 | 0.3 | 1 |
| benign prostatic hyperplasia | 0.6 | 0.3 | 1 |
| Biofilm | 3.5 | 3.5 | |
| Bipolar Disorder | 2.4 | 1.7 | 0.41 |
| Brain Trauma | 0.9 | 1.4 | -0.56 |
| Breast Cancer | 1.2 | 1.2 | |
| Cancer (General) | 0.9 | 3.4 | -2.78 |
| Carcinoma | 4.9 | 2.6 | 0.88 |
| Celiac Disease | 3.6 | 3.8 | -0.06 |
| Cerebral Palsy | 1.4 | 1.3 | 0.08 |
| Chronic Fatigue Syndrome | 6.6 | 7.7 | -0.17 |
| Chronic Kidney Disease | 5.2 | 2.9 | 0.79 |
| Chronic Lyme | 0.6 | 0.8 | -0.33 |
| Chronic Obstructive Pulmonary Disease (COPD) | 3 | 2 | 0.5 |
| Chronic Urticaria (Hives) | 2 | 1.2 | 0.67 |
| Coagulation / Micro clot triggering bacteria | 1.9 | 1.3 | 0.46 |
| Cognitive Function | 3.1 | 1.6 | 0.94 |
| Colorectal Cancer | 7.8 | 2.8 | 1.79 |
| Constipation | 2.1 | 0.7 | 2 |
| Coronary artery disease | 3 | 3 | 0 |
| COVID-19 | 11.5 | 14.3 | -0.24 |
| Crohn's Disease | 9.9 | 5.8 | 0.71 |
| Cushing's Syndrome (hypercortisolism) | 0.9 | -0.9 | |
| cystic fibrosis | 1.2 | 1.9 | -0.58 |
| d-lactic acidosis (one form of brain fog) | 0.6 | 0.6 | |
| deep vein thrombosis | 2.7 | 1.4 | 0.93 |
| Denture Wearers Oral Shifts | 2.1 | 2.1 | |
| Depression | 12.9 | 9.9 | 0.3 |
| Dermatomyositis | 0.3 | 0.3 | 0 |
| Eczema | 2.3 | 2.6 | -0.13 |
| Endometriosis | 3.5 | 2.6 | 0.35 |
| Eosinophilic Esophagitis | 0.3 | 0.6 | -1 |
| Epilepsy | 4 | 1.7 | 1.35 |
| erectile dysfunction | 1.4 | 0.3 | 3.67 |
| Fibromyalgia | 3.7 | 2.6 | 0.42 |
| Functional constipation / chronic idiopathic constipation | 6.9 | 4.9 | 0.41 |
| gallstone disease (gsd) | 4.8 | 1.1 | 3.36 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 2.4 | 1.2 | 1 |
| Generalized anxiety disorder | 3.4 | 2 | 0.7 |
| giant cell arteritis | 0.2 | -0.2 | |
| Glioblastoma | 0.3 | -0.3 | |
| Gout | 2.1 | 0.5 | 3.2 |
| Graves' disease | 1.9 | 3.3 | -0.74 |
| Gulf War Syndrome | 0.9 | 1.5 | -0.67 |
| Halitosis | 1.8 | 0.3 | 5 |
| Hashimoto's thyroiditis | 3.9 | 1.8 | 1.17 |
| Heart Failure | 5.4 | 1.9 | 1.84 |
| hemorrhagic stroke | 1.3 | 1.3 | |
| Hidradenitis Suppurativa | 1.4 | 0.3 | 3.67 |
| High Histamine/low DAO | 1.9 | 0.6 | 2.17 |
| hypercholesterolemia (High Cholesterol) | 1.1 | 1.1 | |
| hyperglycemia | 2.4 | 1.1 | 1.18 |
| Hyperlipidemia (High Blood Fats) | 0.9 | 0.3 | 2 |
| hypersomnia | 0.7 | -0.7 | |
| hypertension (High Blood Pressure | 4.7 | 6.3 | -0.34 |
| Hypothyroidism | 1 | -1 | |
| Hypoxia | 3.6 | 0.3 | 11 |
| IgA nephropathy (IgAN) | 1.9 | 5.5 | -1.89 |
| Inflammatory Bowel Disease | 10.4 | 11 | -0.06 |
| Insomnia | 2.5 | 2.4 | 0.04 |
| Intelligence | 2 | 0.6 | 2.33 |
| Intracranial aneurysms | 1.4 | 0.6 | 1.33 |
| Irritable Bowel Syndrome | 8.9 | 5.3 | 0.68 |
| ischemic stroke | 3.2 | 1.7 | 0.88 |
| Liver Cirrhosis | 8.7 | 4.2 | 1.07 |
| Long COVID | 8.2 | 8.8 | -0.07 |
| Low bone mineral density | 1.1 | -1.1 | |
| Lung Cancer | 1.5 | 1 | 0.5 |
| Lymphoma | 0.6 | 0.6 | |
| Mast Cell Issues / mastitis | 1.5 | 0.9 | 0.67 |
| ME/CFS with IBS | 1.1 | 2.4 | -1.18 |
| ME/CFS without IBS | 2 | 2.4 | -0.2 |
| membranous nephropathy | 0.3 | 0.3 | |
| Menopause | 2.1 | 0.5 | 3.2 |
| Metabolic Syndrome | 9 | 8.5 | 0.06 |
| Mood Disorders | 12.3 | 8.4 | 0.46 |
| multiple chemical sensitivity [MCS] | 1.2 | 0.1 | 11 |
| Multiple Sclerosis | 7.9 | 7 | 0.13 |
| Multiple system atrophy (MSA) | 1.2 | 0.7 | 0.71 |
| myasthenia gravis | 0.9 | 0.7 | 0.29 |
| neuropathic pain | 0.3 | 3.1 | -9.33 |
| Neuropathy (all types) | 0.7 | 2.2 | -2.14 |
| neuropsychiatric disorders (PANDAS, PANS) | 1.2 | 1.2 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 7 | 4.8 | 0.46 |
| NonCeliac Gluten Sensitivity | 1.3 | 0.6 | 1.17 |
| Obesity | 11.1 | 8.9 | 0.25 |
| obsessive-compulsive disorder | 7 | 4.2 | 0.67 |
| Osteoarthritis | 3.3 | 1.2 | 1.75 |
| Osteoporosis | 2.5 | 1.3 | 0.92 |
| pancreatic cancer | 1.2 | 0.3 | 3 |
| Parkinson's Disease | 8.9 | 8.3 | 0.07 |
| Polycystic ovary syndrome | 7.9 | 3.2 | 1.47 |
| Postural orthostatic tachycardia syndrome | 0.2 | 0.6 | -2 |
| Premenstrual dysphoric disorder | 0.7 | 0.4 | 0.75 |
| primary biliary cholangitis | 1.2 | 1.7 | -0.42 |
| Primary sclerosing cholangitis | 3 | 3.2 | -0.07 |
| Psoriasis | 3.9 | 3.4 | 0.15 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 9.6 | 4.7 | 1.04 |
| Rosacea | 1.2 | 1.2 | 0 |
| Schizophrenia | 7.2 | 3.1 | 1.32 |
| scoliosis | 0.9 | 1.2 | -0.33 |
| Sjögren syndrome | 3.2 | 3.2 | 0 |
| Sleep Apnea | 2.2 | 1.8 | 0.22 |
| Slow gastric motility / Gastroparesis | 1.5 | 0.3 | 4 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 2.2 | 0.6 | 2.67 |
| Stress / posttraumatic stress disorder | 3.2 | 2.7 | 0.19 |
| Systemic Lupus Erythematosus | 4.9 | 2.4 | 1.04 |
| Tic Disorder | 1.5 | 1.8 | -0.2 |
| Tourette syndrome | 0.9 | 0.3 | 2 |
| Type 1 Diabetes | 5 | 4.4 | 0.14 |
| Type 2 Diabetes | 10 | 7.9 | 0.27 |
| Ulcerative colitis | 7.5 | 7.7 | -0.03 |
| Unhealthy Ageing | 6.8 | 2.4 | 1.83 |
| Vitiligo | 2.5 | 1.5 | 0.67 |
