Bacterial Infections: Cephalothin sodium salt is effective against a variety of bacterial infections caused by susceptible organisms, including:
Respiratory tract infections: Such as pneumonia, bronchitis, and lung abscess.
Skin and soft tissue infections: Including cellulitis, wound infections, and surgical site infections.
Urinary tract infections (UTIs): Including cystitis and pyelonephritis.
Bone and joint infections: Such as osteomyelitis and septic arthritis.
Intra-abdominal infections: Including peritonitis and cholecystitis.
Bacterial endocarditis: In some cases, cephalothin may be used prophylactically in patients undergoing certain surgical procedures to prevent bacterial endocarditis.
Dosage and Administration: The dosage and administration of cephalothin sodium salt depend on factors such as the type and severity of the infection, the patient's age and weight, renal function, and bacterial susceptibility patterns. It is typically administered via intravenous or intramuscular injection.
Adverse Effects: Common side effects of cephalothin sodium salt may include:
Gastrointestinal disturbances: Such as nausea, vomiting, diarrhea, and abdominal pain.
Hypersensitivity reactions: Including rash, itching, and hives. Severe allergic reactions such as anaphylaxis are rare but possible.
Superinfections: Prolonged or repeated use of cephalothin sodium salt may result in the overgrowth of nonsusceptible organisms, leading to secondary infections such as fungal or Clostridium difficile-associated colitis.
Hematologic abnormalities: Such as leukopenia, neutropenia, and thrombocytopenia.
Renal toxicity: Rarely, cephalothin sodium salt may cause renal dysfunction, especially at high doses or in patients with preexisting renal impairment.
Drug Interactions: Cephalothin sodium salt may interact with other medications, particularly those affecting renal function or interfering with the absorption of antibiotics. Clinicians should exercise caution when administering cephalothin sodium salt concurrently with other drugs to avoid potential interactions.
Resistant Bacteria: Overuse or inappropriate use of cephalothin sodium salt can lead to the development of bacterial resistance, reducing its effectiveness in treating infections.
Bacteria Impacted by cephalothin sodium salt (antibiotic)
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Impact of cephalothin sodium salt (antibiotic) on Conditions from US National Library of Medicine
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups.
We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio: Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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