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Bacterial Infections: Cefmetazole is effective against a wide range of Gram-positive and Gram-negative bacteria. It is commonly used to treat infections caused by organisms such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter species, and Streptococcus species.
Intra-abdominal Infections: Cefmetazole is particularly useful in the treatment of intra-abdominal infections, including peritonitis and abscesses. It can penetrate well into abdominal tissues and effectively target the causative bacteria.
Urinary Tract Infections: Cefmetazole is also used to treat urinary tract infections (UTIs), including cystitis and pyelonephritis. It can eradicate bacteria commonly responsible for UTIs, such as Escherichia coli and Klebsiella pneumoniae.
Respiratory Tract Infections: In some cases, cefmetazole may be prescribed to treat respiratory tract infections, including pneumonia and bronchitis, particularly when caused by susceptible bacteria.
Skin and Soft Tissue Infections: Cefmetazole can be used to treat certain skin and soft tissue infections caused by susceptible bacteria. It may be prescribed for cellulitis, wound infections, and other similar conditions.
Surgical Prophylaxis: Cefmetazole is often used prophylactically to prevent surgical site infections in procedures such as colorectal surgery, gynecological surgery, and abdominal surgery.
Dosage and Administration: Cefmetazole is typically administered intravenously, either as a bolus injection or by continuous infusion. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's age, weight, and renal function.
Adverse Effects: Common side effects of cefmetazole may include gastrointestinal symptoms such as diarrhea, nausea, vomiting, and abdominal pain. Allergic reactions, including rash, itching, and swelling, can occur, although they are relatively rare.
Drug Interactions: Cefmetazole may interact with other medications, particularly those that affect renal function or interfere with the absorption of antibiotics. It is essential to review the patient's medication history and potential drug interactions before prescribing cefmetazole.
Resistance: Bacterial resistance to cefmetazole is a concern, particularly in regions where antibiotic use is widespread. Resistance can develop due to overuse or misuse of antibiotics, making treatment less effective over time.
Pediatric and Geriatric Use: Cefmetazole can be used in pediatric and geriatric populations, although dosage adjustments may be necessary based on age, weight, and renal function.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.