🍽️ ketoconazole,(prescription)

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Antifungal Activity: Ketoconazole works by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes. This action disrupts the integrity of the fungal cell membrane, leading to cell death and clearance of the infection. It is effective against a wide range of fungal pathogens, including dermatophytes, yeasts, and molds.
Fungal Skin Infections: Ketoconazole is commonly prescribed for the treatment of fungal skin infections such as tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete's foot), and tinea versicolor (a fungal infection that affects the skin's coloration). It helps alleviate symptoms like itching, redness, and scaling associated with these infections.
Seborrheic Dermatitis: Ketoconazole is also used to manage seborrheic dermatitis, a chronic inflammatory skin condition characterized by red, scaly patches on the scalp, face, and other areas rich in sebaceous glands. It helps control the growth of Malassezia yeasts, which are believed to contribute to the development of seborrheic dermatitis.
Dandruff: Ketoconazole-containing shampoos are available over the counter for the treatment of dandruff caused by Malassezia yeasts. Regular use of ketoconazole shampoo can help reduce flaking, itching, and inflammation associated with dandruff.
Oral and Systemic Infections: In addition to topical formulations, ketoconazole is available in oral tablets for the treatment of systemic fungal infections such as candidiasis (yeast infection), histoplasmosis, and blastomycosis. Oral ketoconazole is reserved for severe or recurrent infections that do not respond to topical treatments or for infections that affect internal organs.
Off-label Uses: Ketoconazole may be used off-label for the treatment of other conditions, including fungal infections of the nails (onychomycosis), pityriasis versicolor, and as part of combination therapy for conditions like chronic mucocutaneous candidiasis.
Adverse Effects: Common side effects of ketoconazole may include skin irritation, burning, itching, dryness, and rash at the application site. Oral ketoconazole can cause gastrointestinal upset, headache, dizziness, and liver enzyme abnormalities. Rare but serious adverse effects include hepatotoxicity (liver damage) and adrenal insufficiency.
Precautions: Ketoconazole should be used with caution in individuals with liver disease, impaired adrenal function, or a history of hypersensitivity reactions to azole antifungal agents. Long-term or high-dose use of oral ketoconazole should be avoided due to the risk of serious side effects.
Drug Interactions: Ketoconazole can interact with a wide range of medications, including certain anticoagulants, anticonvulsants, statins, and immunosuppressants. It may increase the risk of adverse effects or alter the metabolism of co-administered drugs.
Pregnancy and Lactation: The safety of ketoconazole use during pregnancy and breastfeeding has not been well established. Pregnant or nursing women should consult their healthcare providers before using ketoconazole to weigh the potential benefits against the risks.

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Data Contradictions — Limits of Certainity

Impacted of ketoconazole,(prescription) On Probiotics

Rank	Probiotic	Impact
genus	Bifidobacterium	Reduces
species	Bacteroides uniformis	Reduces
species	Bifidobacterium adolescentis	Reduces
species	Bifidobacterium longum	Reduces
species	Escherichia coli	Reduces
species	Lacticaseibacillus paracasei	Reduces
species	Parabacteroides distasonis	Reduces
subspecies	Bifidobacterium longum subsp. infantis	Reduces
subspecies	Bifidobacterium longum subsp. longum	Reduces

Bacteria Impacted by ketoconazole,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy	Rank	Effect	Citations	Notation
Malasseziaceae	family	Decreases	👪 Source Study
Escherichia	genus	Decreases	👪 Source Study
Escherichia	genus	Decreases	👪 Source Study
Dorea	genus	Decreases	👪 Source Study
Roseburia	genus	Decreases	👪 Source Study
Roseburia	genus	Decreases	👪 Source Study
Malassezia	genus	Decreases	📓 Source Study
Parabacteroides	genus	Decreases	👪 Source Study	BMI, fat percent,blood pressure
Ruminococcus	genus	Decreases	👪 Source Study
Agathobacter	genus	Decreases	👪 Source Study
Agathobacter	genus	Decreases	👪 Source Study
Bacteroides	genus	Decreases	👪 Source Study
Bacteroides	genus	Decreases	👪 Source Study
Bifidobacterium	genus	Decreases	👪 Source Study
Bilophila	genus	Decreases	👪 Source Study	High Level Cause Brain Fog(Cognitive impairment)
Clostridioides	genus	Decreases	👪 Source Study
Collinsella	genus	Decreases	👪 Source Study	proinflammatory
Coprococcus	genus	Decreases	👪 Source Study
Eggerthella	genus	Decreases	👪 Source Study
Fusobacterium	genus	Decreases	👪 Source Study	Periodontal disease, Lemierre syndrome, skin ulcers
Lachnospira	genus	Decreases	👪 Source Study
Lacrimispora	genus	Decreases	👪 Source Study
Mediterraneibacter	genus	Decreases	👪 Source Study
Odoribacter	genus	Decreases	👪 Source Study
Phocaeicola	genus	Decreases	👪 Source Study
Phocaeicola	genus	Decreases	👪 Source Study
Streptococcus	genus	Decreases	👪 Source Study
Clostridium	genus	Decreases	👪 Source Study	Pathogen
Clostridium	genus	Decreases	👪 Source Study	Pathogen
Segatella	genus	Decreases	👪 Source Study
Segatella	genus	Decreases	👪 Source Study
Enterocloster	genus	Decreases	👪 Source Study
Enterocloster	genus	Decreases	👪 Source Study
Blautia	genus	Decreases	👪 Source Study
Thomasclavelia	genus	Decreases	👪 Source Study
Lacticaseibacillus	genus	Decreases	👪 Source Study
Escherichia coli O25:H16	no rank	Decreases	👶 Source Study
Escherichia coli O25:H16	no rank	Decreases	👶 Source Study
Clostridium perfringens A	no rank	Decreases	👶 Source Study
Clostridium perfringens A	no rank	Decreases	👶 Source Study
Clostridium perfringens C	no rank	Decreases	👶 Source Study
Clostridium perfringens C	no rank	Decreases	👶 Source Study
Clostridium perfringens CPE	no rank	Decreases	👶 Source Study
Clostridium perfringens CPE	no rank	Decreases	👶 Source Study
Escherichia coli O145:H34	no rank	Decreases	👶 Source Study
Escherichia coli O145:H34	no rank	Decreases	👶 Source Study
Escherichia coli O16:H48	no rank	Decreases	👶 Source Study
Escherichia coli O16:H48	no rank	Decreases	👶 Source Study
Clostridium perfringens D	no rank	Decreases	👶 Source Study
Clostridium perfringens D	no rank	Decreases	👶 Source Study
Escherichia coli O141:H4	no rank	Decreases	👶 Source Study
Escherichia coli O141:H4	no rank	Decreases	👶 Source Study
Clostridium perfringens B	no rank	Decreases	👶 Source Study
Clostridium perfringens B	no rank	Decreases	👶 Source Study
Escherichia coli O139:H1	no rank	Decreases	👶 Source Study
Escherichia coli O139:H1	no rank	Decreases	👶 Source Study
Clostridium perfringens E	no rank	Decreases	👶 Source Study
Clostridium perfringens E	no rank	Decreases	👶 Source Study
Escherichia coli O80:H26	no rank	Decreases	👶 Source Study
Escherichia coli O80:H26	no rank	Decreases	👶 Source Study
Escherichia coli O158:H23	no rank	Decreases	👶 Source Study
Escherichia coli O158:H23	no rank	Decreases	👶 Source Study
Escherichia coli O84:H7	no rank	Decreases	👶 Source Study
Escherichia coli O84:H7	no rank	Decreases	👶 Source Study
Escherichia coli O2:K1:H4	no rank	Decreases	👶 Source Study
Escherichia coli O2:K1:H4	no rank	Decreases	👶 Source Study
Escherichia coli O2:K1:H7	no rank	Decreases	👶 Source Study
Escherichia coli O2:K1:H7	no rank	Decreases	👶 Source Study
Escherichia coli O78:H51	no rank	Decreases	👶 Source Study
Escherichia coli O78:H51	no rank	Decreases	👶 Source Study
Escherichia coli O18ac:H14	no rank	Decreases	👶 Source Study
Escherichia coli O18ac:H14	no rank	Decreases	👶 Source Study
Escherichia coli O85:H1	no rank	Decreases	👶 Source Study
Escherichia coli O85:H1	no rank	Decreases	👶 Source Study
Escherichia coli O7:H15	no rank	Decreases	👶 Source Study
Escherichia coli O7:H15	no rank	Decreases	👶 Source Study
Escherichia coli O68:H12	no rank	Decreases	👶 Source Study
Escherichia coli O68:H12	no rank	Decreases	👶 Source Study
Escherichia coli O55:H7	no rank	Decreases	👶 Source Study
Escherichia coli O55:H7	no rank	Decreases	👶 Source Study
Escherichia coli O1:K1:H7	no rank	Decreases	👶 Source Study
Escherichia coli O1:K1:H7	no rank	Decreases	👶 Source Study
Escherichia coli O15:H12	no rank	Decreases	👶 Source Study
Escherichia coli O15:H12	no rank	Decreases	👶 Source Study
Escherichia coli O170:H18	no rank	Decreases	👶 Source Study
Escherichia coli O170:H18	no rank	Decreases	👶 Source Study
Escherichia coli O155:H21	no rank	Decreases	👶 Source Study
Escherichia coli O155:H21	no rank	Decreases	👶 Source Study
Escherichia coli O19:H7	no rank	Decreases	👶 Source Study
Escherichia coli O19:H7	no rank	Decreases	👶 Source Study
Escherichia coli O2:K1:H5	no rank	Decreases	👶 Source Study
Escherichia coli O2:K1:H5	no rank	Decreases	👶 Source Study
Escherichia coli O20:H12	no rank	Decreases	👶 Source Study
Escherichia coli O20:H12	no rank	Decreases	👶 Source Study
Escherichia coli O111	serogroup	Decreases	👶 Source Study
Escherichia coli O111	serogroup	Decreases	👶 Source Study
Escherichia coli O121	serogroup	Decreases	👶 Source Study
Escherichia coli O121	serogroup	Decreases	👶 Source Study
Escherichia coli O155	serogroup	Decreases	👶 Source Study
Escherichia coli O155	serogroup	Decreases	👶 Source Study
Escherichia coli O177	serogroup	Decreases	👶 Source Study
Escherichia coli O177	serogroup	Decreases	👶 Source Study
Escherichia coli O26	serogroup	Decreases	👶 Source Study
Escherichia coli O26	serogroup	Decreases	👶 Source Study
Escherichia coli O3	serogroup	Decreases	👶 Source Study
Escherichia coli O3	serogroup	Decreases	👶 Source Study
Escherichia coli O5	serogroup	Decreases	👶 Source Study
Escherichia coli O5	serogroup	Decreases	👶 Source Study
Escherichia coli O86	serogroup	Decreases	👶 Source Study
Escherichia coli O86	serogroup	Decreases	👶 Source Study
Escherichia coli O91	serogroup	Decreases	👶 Source Study
Escherichia coli O91	serogroup	Decreases	👶 Source Study
Escherichia coli O103	serogroup	Decreases	👶 Source Study
Escherichia coli O103	serogroup	Decreases	👶 Source Study
Escherichia coli O78	serogroup	Decreases	👶 Source Study
Escherichia coli O78	serogroup	Decreases	👶 Source Study
Escherichia coli O43	serogroup	Decreases	👶 Source Study
Escherichia coli O43	serogroup	Decreases	👶 Source Study
Escherichia coli O119	serogroup	Decreases	👶 Source Study
Escherichia coli O119	serogroup	Decreases	👶 Source Study
Escherichia coli O157	serogroup	Decreases	👶 Source Study
Escherichia coli O157	serogroup	Decreases	👶 Source Study
Escherichia coli O145	serogroup	Decreases	👶 Source Study
Escherichia coli O145	serogroup	Decreases	👶 Source Study
Escherichia coli O1:HNT	serotype	Decreases	👶 Source Study
Escherichia coli O1:HNT	serotype	Decreases	👶 Source Study
Escherichia coli O10:K5(L):H4	serotype	Decreases	👶 Source Study
Escherichia coli O10:K5(L):H4	serotype	Decreases	👶 Source Study
Escherichia coli O103:H11	serotype	Decreases	👶 Source Study
Escherichia coli O103:H11	serotype	Decreases	👶 Source Study
Escherichia coli O103:H25	serotype	Decreases	👶 Source Study
Escherichia coli O103:H25	serotype	Decreases	👶 Source Study
Escherichia coli O104:H21	serotype	Decreases	👶 Source Study
Escherichia coli O104:H21	serotype	Decreases	👶 Source Study
Escherichia coli O111:H11	serotype	Decreases	👶 Source Study
Escherichia coli O111:H11	serotype	Decreases	👶 Source Study
Escherichia coli O111:H8	serotype	Decreases	👶 Source Study
Escherichia coli O111:H8	serotype	Decreases	👶 Source Study
Escherichia coli O112ac:H19	serotype	Decreases	👶 Source Study
Escherichia coli O112ac:H19	serotype	Decreases	👶 Source Study
Escherichia coli O114:H49	serotype	Decreases	👶 Source Study
Escherichia coli O114:H49	serotype	Decreases	👶 Source Study
Escherichia coli O118:H16	serotype	Decreases	👶 Source Study
Escherichia coli O118:H16	serotype	Decreases	👶 Source Study
Escherichia coli O121:H7	serotype	Decreases	👶 Source Study
Escherichia coli O121:H7	serotype	Decreases	👶 Source Study
Escherichia coli O123:H11	serotype	Decreases	👶 Source Study
Escherichia coli O123:H11	serotype	Decreases	👶 Source Study
Escherichia coli O127:H27	serotype	Decreases	👶 Source Study
Escherichia coli O127:H27	serotype	Decreases	👶 Source Study
Escherichia coli O127:H6	serotype	Decreases	👶 Source Study
Escherichia coli O127:H6	serotype	Decreases	👶 Source Study
Escherichia coli O128:H2	serotype	Decreases	👶 Source Study
Escherichia coli O128:H2	serotype	Decreases	👶 Source Study
Escherichia coli O128ac:H12	serotype	Decreases	👶 Source Study
Escherichia coli O128ac:H12	serotype	Decreases	👶 Source Study
Escherichia coli O145:H25	serotype	Decreases	👶 Source Study
Escherichia coli O145:H25	serotype	Decreases	👶 Source Study
Escherichia coli O145:NM	serotype	Decreases	👶 Source Study
Escherichia coli O145:NM	serotype	Decreases	👶 Source Study
Escherichia coli O146:H21	serotype	Decreases	👶 Source Study
Escherichia coli O146:H21	serotype	Decreases	👶 Source Study
Escherichia coli O153:H2	serotype	Decreases	👶 Source Study
Escherichia coli O153:H2	serotype	Decreases	👶 Source Study
Escherichia coli O156:H25	serotype	Decreases	👶 Source Study
Escherichia coli O156:H25	serotype	Decreases	👶 Source Study
Escherichia coli O157:H43	serotype	Decreases	👶 Source Study
Escherichia coli O157:H43	serotype	Decreases	👶 Source Study
Escherichia coli O157:NM	serotype	Decreases	👶 Source Study
Escherichia coli O157:NM	serotype	Decreases	👶 Source Study
Escherichia coli O165:H25	serotype	Decreases	👶 Source Study
Escherichia coli O165:H25	serotype	Decreases	👶 Source Study
Escherichia coli O174:H2	serotype	Decreases	👶 Source Study
Escherichia coli O174:H2	serotype	Decreases	👶 Source Study
Escherichia coli O174:H21	serotype	Decreases	👶 Source Study
Escherichia coli O174:H21	serotype	Decreases	👶 Source Study
Escherichia coli O174:H8	serotype	Decreases	👶 Source Study
Escherichia coli O174:H8	serotype	Decreases	👶 Source Study
Escherichia coli O176:H45	serotype	Decreases	👶 Source Study
Escherichia coli O176:H45	serotype	Decreases	👶 Source Study
Escherichia coli O177:NM	serotype	Decreases	👶 Source Study
Escherichia coli O177:NM	serotype	Decreases	👶 Source Study
Escherichia coli O26:H1	serotype	Decreases	👶 Source Study
Escherichia coli O26:H1	serotype	Decreases	👶 Source Study
Escherichia coli O28ac:NM	serotype	Decreases	👶 Source Study
Escherichia coli O28ac:NM	serotype	Decreases	👶 Source Study
Escherichia coli O29:H4	serotype	Decreases	👶 Source Study
Escherichia coli O29:H4	serotype	Decreases	👶 Source Study
Escherichia coli O32:H37	serotype	Decreases	👶 Source Study
Escherichia coli O32:H37	serotype	Decreases	👶 Source Study
Escherichia coli O6:H16:CFA/II	serotype	Decreases	👶 Source Study
Escherichia coli O6:H16:CFA/II	serotype	Decreases	👶 Source Study
Escherichia coli O69:H11	serotype	Decreases	👶 Source Study
Escherichia coli O69:H11	serotype	Decreases	👶 Source Study
Escherichia coli O78:H12	serotype	Decreases	👶 Source Study
Escherichia coli O78:H12	serotype	Decreases	👶 Source Study
Escherichia coli O79:H7	serotype	Decreases	👶 Source Study
Escherichia coli O79:H7	serotype	Decreases	👶 Source Study
Escherichia coli O81:NM	serotype	Decreases	👶 Source Study
Escherichia coli O81:NM	serotype	Decreases	👶 Source Study
Escherichia coli O86:H34	serotype	Decreases	👶 Source Study
Escherichia coli O86:H34	serotype	Decreases	👶 Source Study
Escherichia coli O91:H14	serotype	Decreases	👶 Source Study
Escherichia coli O91:H14	serotype	Decreases	👶 Source Study
Escherichia coli O91:NM	serotype	Decreases	👶 Source Study
Escherichia coli O91:NM	serotype	Decreases	👶 Source Study
Escherichia coli ONT:H33	serotype	Decreases	👶 Source Study
Escherichia coli ONT:H33	serotype	Decreases	👶 Source Study
Escherichia coli O100:H21	serotype	Decreases	👶 Source Study
Escherichia coli O100:H21	serotype	Decreases	👶 Source Study
Escherichia coli O121:H19	serotype	Decreases	👶 Source Study
Escherichia coli O121:H19	serotype	Decreases	👶 Source Study
Escherichia coli O157:H7	serotype	Decreases	👶 Source Study	bloody diarrhea
Escherichia coli O157:H7	serotype	Decreases	👶 Source Study	bloody diarrhea
Escherichia coli O16:H6	serotype	Decreases	👶 Source Study
Escherichia coli O16:H6	serotype	Decreases	👶 Source Study
Escherichia coli O89m:H9	serotype	Decreases	👶 Source Study
Escherichia coli O89m:H9	serotype	Decreases	👶 Source Study
Escherichia coli O111:H-	serotype	Decreases	👶 Source Study
Escherichia coli O111:H-	serotype	Decreases	👶 Source Study
Escherichia coli O113:H21	serotype	Decreases	👶 Source Study
Escherichia coli O113:H21	serotype	Decreases	👶 Source Study
Escherichia coli H20	serotype	Decreases	👶 Source Study
Escherichia coli H20	serotype	Decreases	👶 Source Study
Escherichia coli O150:H6	serotype	Decreases	👶 Source Study
Escherichia coli O150:H6	serotype	Decreases	👶 Source Study
Escherichia coli O111:NM	serotype	Decreases	👶 Source Study
Escherichia coli O111:NM	serotype	Decreases	👶 Source Study
Escherichia coli O112ab:H8	serotype	Decreases	👶 Source Study
Escherichia coli O112ab:H8	serotype	Decreases	👶 Source Study
Escherichia coli O99:H6	serotype	Decreases	👶 Source Study
Escherichia coli O99:H6	serotype	Decreases	👶 Source Study
Escherichia coli O26:H11	serotype	Decreases	👶 Source Study
Escherichia coli O26:H11	serotype	Decreases	👶 Source Study
Escherichia coli O145:H28	serotype	Decreases	👶 Source Study
Escherichia coli O145:H28	serotype	Decreases	👶 Source Study
Escherichia coli O126:H45	serotype	Decreases	👶 Source Study
Escherichia coli O126:H45	serotype	Decreases	👶 Source Study
Escherichia coli O2:H6	serotype	Decreases	👶 Source Study
Escherichia coli O2:H6	serotype	Decreases	👶 Source Study
Escherichia coli O7:H4	serotype	Decreases	👶 Source Study
Escherichia coli O7:H4	serotype	Decreases	👶 Source Study
Escherichia coli O1:H42	serotype	Decreases	👶 Source Study
Escherichia coli O1:H42	serotype	Decreases	👶 Source Study
Escherichia coli O25:NM	serotype	Decreases	👶 Source Study
Escherichia coli O25:NM	serotype	Decreases	👶 Source Study
Escherichia coli O25:H1	serotype	Decreases	👶 Source Study
Escherichia coli O25:H1	serotype	Decreases	👶 Source Study
Escherichia coli O7:K1	serotype	Decreases	👶 Source Study
Escherichia coli O7:K1	serotype	Decreases	👶 Source Study
Escherichia coli O125ac:K+:H10	serotype	Decreases	👶 Source Study
Escherichia coli O125ac:K+:H10	serotype	Decreases	👶 Source Study
Escherichia coli O6:K2:H1	serotype	Decreases	👶 Source Study
Escherichia coli O6:K2:H1	serotype	Decreases	👶 Source Study
Escherichia coli O152:H23	serotype	Decreases	👶 Source Study
Escherichia coli O152:H23	serotype	Decreases	👶 Source Study
Escherichia coli O15:H18	serotype	Decreases	👶 Source Study
Escherichia coli O15:H18	serotype	Decreases	👶 Source Study
Escherichia coli O39:NM	serotype	Decreases	👶 Source Study
Escherichia coli O39:NM	serotype	Decreases	👶 Source Study
Escherichia coli O44:H18	serotype	Decreases	👶 Source Study
Escherichia coli O44:H18	serotype	Decreases	👶 Source Study
Escherichia coli O2:K2:H1	serotype	Decreases	👶 Source Study
Escherichia coli O2:K2:H1	serotype	Decreases	👶 Source Study
Escherichia coli O8:H8	serotype	Decreases	👶 Source Study
Escherichia coli O8:H8	serotype	Decreases	👶 Source Study
Escherichia coli O89m:H10	serotype	Decreases	👶 Source Study
Escherichia coli O89m:H10	serotype	Decreases	👶 Source Study
Escherichia coli O10:H32	serotype	Decreases	👶 Source Study
Escherichia coli O10:H32	serotype	Decreases	👶 Source Study
Escherichia coli O6:H16	serotype	Decreases	👶 Source Study
Escherichia coli O6:H16	serotype	Decreases	👶 Source Study
Escherichia coli O157:H-	serotype	Decreases	👶 Source Study
Escherichia coli O157:H-	serotype	Decreases	👶 Source Study
Escherichia coli O45:H2	serotype	Decreases	👶 Source Study
Escherichia coli O45:H2	serotype	Decreases	👶 Source Study
Escherichia coli O103:H2	serotype	Decreases	👶 Source Study
Escherichia coli O103:H2	serotype	Decreases	👶 Source Study
Escherichia coli O167:H26	serotype	Decreases	👶 Source Study
Escherichia coli O167:H26	serotype	Decreases	👶 Source Study
Escherichia coli O104:H4	serotype	Decreases	👶 Source Study
Escherichia coli O104:H4	serotype	Decreases	👶 Source Study
Escherichia coli O83:H1	serotype	Decreases	👶 Source Study
Escherichia coli O83:H1	serotype	Decreases	👶 Source Study
Escherichia coli O9:H10	serotype	Decreases	👶 Source Study
Escherichia coli O9:H10	serotype	Decreases	👶 Source Study
Escherichia coli O78:H4	serotype	Decreases	👶 Source Study
Escherichia coli O78:H4	serotype	Decreases	👶 Source Study
Escherichia coli O139:H28	serotype	Decreases	👶 Source Study
Escherichia coli O139:H28	serotype	Decreases	👶 Source Study
Bacteroides ovatus	species	Decreases	📓 Source Study
Odoribacter splanchnicus	species	Decreases	📓 Source Study
Escherichia coli	species	Decreases	📓 Source Study	Diarrheal disease in children and travelers, Foodborne diarrhea outbreaks, hemorrhagic colitis, hemolytic-uremic syndrome
Bacteroides caccae	species	Decreases	📓 Source Study
[Ruminococcus] torques	species	Decreases	📓 Source Study
Agathobacter rectalis	species	Decreases	📓 Source Study
Bacteroides fragilis	species	Decreases	📓 Source Study	H02076 Bacteroides infection
Bacteroides uniformis	species	Decreases	📓 Source Study	Infectious bacteria
Bifidobacterium adolescentis	species	Decreases	📓 Source Study
Blautia obeum	species	Decreases	📓 Source Study
Clostridium perfringens	species	Decreases	📓 Source Study	Food poisoning, gas gangrene
Collinsella aerofaciens	species	Decreases	📓 Source Study
Coprococcus comes	species	Decreases	📓 Source Study
Dorea formicigenerans	species	Decreases	📓 Source Study
Eggerthella lenta	species	Decreases	📓 Source Study
Fusobacterium nucleatum	species	Decreases	📓 Source Study	Infectious bacteria
Lachnospira eligens	species	Decreases	📓 Source Study
Lacticaseibacillus paracasei	species	Decreases	📓 Source Study
Mediterraneibacter gnavus	species	Decreases	📓 Source Study
Parabacteroides distasonis	species	Decreases	📓 Source Study
Parabacteroides merdae	species	Decreases	📓 Source Study	Infectious bacteria
Phocaeicola vulgatus	species	Decreases	📓 Source Study
Roseburia intestinalis	species	Decreases	📓 Source Study
Ruminococcus bromii	species	Decreases	📓 Source Study
Segatella copri	species	Decreases	📓 Source Study	Over 70%ile Indicator of mycotoxin present
Malassezia restricta	species	Decreases	👶 Source Study
Thomasclavelia ramosa	species	Decreases	📓 Source Study
Agathobacter rectalis	species	Decreases	📓 Source Study
Bacteroides caccae	species	Decreases	📓 Source Study
Bacteroides fragilis	species	Decreases	📓 Source Study	H02076 Bacteroides infection
Bacteroides ovatus	species	Decreases	📓 Source Study
Bacteroides thetaiotaomicron	species	Decreases	📓 Source Study
Bacteroides uniformis	species	Decreases	📓 Source Study	Infectious bacteria
Bacteroides xylanisolvens	species	Decreases	📓 Source Study
Clostridioides difficile	species	Decreases	📓 Source Study	Colitis
Clostridium perfringens	species	Decreases	📓 Source Study	Food poisoning, gas gangrene
Enterocloster bolteae	species	Decreases	📓 Source Study
Escherichia coli	species	Decreases	📓 Source Study	Diarrheal disease in children and travelers, Foodborne diarrhea outbreaks, hemorrhagic colitis, hemolytic-uremic syndrome
Phocaeicola vulgatus	species	Decreases	📓 Source Study
Roseburia intestinalis	species	Decreases	📓 Source Study
Segatella copri	species	Decreases	📓 Source Study	Over 70%ile Indicator of mycotoxin present
Lacrimispora saccharolytica	species	Decreases	📓 Source Study
Streptococcus parasanguinis	species	Decreases	📓 Source Study
Roseburia hominis	species	Decreases	📓 Source Study
Streptococcus salivarius	species	Decreases	📓 Source Study	Infectious bacteria
Fusobacterium nucleatum	species	Decreases	👪 Source Study	Infectious bacteria
Malassezia furfur	species	Decreases	👶 Source Study
Malassezia globosa	species	Decreases	👶 Source Study
Malassezia obtusa	species	Decreases	👶 Source Study
Malassezia pachydermatis	species	Decreases	👶 Source Study
Malassezia sympodialis	species	Decreases	👶 Source Study
Enterocloster bolteae	species	Decreases	📓 Source Study
Bacteroides thetaiotaomicron	species	Decreases	📓 Source Study
Bilophila wadsworthia	species	Decreases	📓 Source Study
Bifidobacterium longum	species	Decreases	📓 Source Study
Segatella copri DSM 18205	strain	Decreases	👶 Source Study
Roseburia intestinalis M50/1	strain	Decreases	👶 Source Study
Roseburia intestinalis XB6B4	strain	Decreases	👶 Source Study
Bacteroides uniformis CL03T12C37	strain	Decreases	👶 Source Study
Bacteroides caccae CL03T12C61	strain	Decreases	👶 Source Study
Escherichia coli ECC-1470	strain	Decreases	👶 Source Study
Fusobacterium nucleatum subsp. nucleatum ATCC 23726	strain	Decreases	👶 Source Study
Roseburia intestinalis L1-82	strain	Decreases	👶 Source Study
Agathobacter rectalis ATCC 33656	strain	Decreases	👶 Source Study
Agathobacter rectalis DSM 17629	strain	Decreases	👶 Source Study
Agathobacter rectalis M104/1	strain	Decreases	👶 Source Study
Bacteroides caccae ATCC 43185	strain	Decreases	👶 Source Study
Bacteroides fragilis HMW 615	strain	Decreases	👶 Source Study
Bacteroides fragilis NCTC 9343	strain	Decreases	👶 Source Study	H02076 Bacteroides infection
Bacteroides fragilis str. 3397 T10	strain	Decreases	👶 Source Study
Bacteroides fragilis str. 3725 D9 ii	strain	Decreases	👶 Source Study
Bacteroides fragilis str. 3976T8	strain	Decreases	👶 Source Study
Bacteroides fragilis str. 3988T(B)14	strain	Decreases	👶 Source Study
Bacteroides fragilis str. 3998 T(B) 4	strain	Decreases	👶 Source Study
Bacteroides fragilis str. 3-F-2 #6	strain	Decreases	👶 Source Study
Bacteroides fragilis str. I1345	strain	Decreases	👶 Source Study
Bacteroides ovatus 3_8_47FAA	strain	Decreases	👶 Source Study
Bacteroides ovatus ATCC 8483	strain	Decreases	👶 Source Study
Bacteroides ovatus CL02T12C04	strain	Decreases	👶 Source Study
Bacteroides ovatus CL03T12C18	strain	Decreases	👶 Source Study
Bacteroides ovatus SD CMC 3f	strain	Decreases	👶 Source Study
Bacteroides ovatus str. 3725 D1 iv	strain	Decreases	👶 Source Study
Bacteroides thetaiotaomicron dnLKV9	strain	Decreases	👶 Source Study
Bacteroides uniformis ATCC 8492	strain	Decreases	👶 Source Study
Bacteroides uniformis CL03T00C23	strain	Decreases	👶 Source Study
Bacteroides uniformis dnLKV2	strain	Decreases	👶 Source Study
Bacteroides uniformis str. 3978 T3 i	strain	Decreases	👶 Source Study
Bacteroides uniformis str. 3978 T3 ii	strain	Decreases	👶 Source Study
Bacteroides xylanisolvens CL03T12C04	strain	Decreases	👶 Source Study
Bacteroides xylanisolvens SD CC 1b	strain	Decreases	👶 Source Study
Bacteroides xylanisolvens SD CC 2a	strain	Decreases	👶 Source Study
Clostridioides difficile 002-P50-2011	strain	Decreases	👶 Source Study
Clostridioides difficile 2007855	strain	Decreases	👶 Source Study
Clostridioides difficile 342	strain	Decreases	👶 Source Study
Clostridioides difficile 6041	strain	Decreases	👶 Source Study
Clostridioides difficile 630	strain	Decreases	👶 Source Study	H00338 Pseudomembranous colitis
Clostridioides difficile ATCC 9689 = DSM 1296	strain	Decreases	👶 Source Study
Clostridioides difficile BJ08	strain	Decreases	👶 Source Study
Clostridioides difficile CD196	strain	Decreases	👶 Source Study	H00338 Pseudomembranous colitis
Clostridioides difficile CD40	strain	Decreases	👶 Source Study
Clostridioides difficile DA00195	strain	Decreases	👶 Source Study
Clostridioides difficile E85	strain	Decreases	👶 Source Study
Clostridioides difficile F321	strain	Decreases	👶 Source Study
Clostridioides difficile F501	strain	Decreases	👶 Source Study
Clostridioides difficile genomovar ribotype_087	strain	Decreases	👶 Source Study
Clostridioides difficile M120	strain	Decreases	👶 Source Study
Clostridioides difficile NAP08	strain	Decreases	👶 Source Study
Clostridioides difficile P28	strain	Decreases	👶 Source Study
Clostridioides difficile P29	strain	Decreases	👶 Source Study
Clostridioides difficile P38	strain	Decreases	👶 Source Study
Clostridioides difficile P51	strain	Decreases	👶 Source Study
Clostridioides difficile QCD-76w55	strain	Decreases	👶 Source Study
Clostridium perfringens SM101	strain	Decreases	👶 Source Study	H00335 Foodborne Clostridium perfringens intoxication
Enterocloster bolteae 90A5	strain	Decreases	👶 Source Study
Enterocloster bolteae 90A9	strain	Decreases	👶 Source Study
Enterocloster bolteae 90B3	strain	Decreases	👶 Source Study
Enterocloster bolteae 90B8	strain	Decreases	👶 Source Study
Enterocloster bolteae ATCC BAA-613	strain	Decreases	👶 Source Study
Enterocloster bolteae CAG:59	strain	Decreases	👶 Source Study
Escherichia coli APEC IMT5155	strain	Decreases	👶 Source Study
Escherichia coli B str. REL606	strain	Decreases	👶 Source Study
Escherichia coli 'BL21-Gold(DE3)pLysS AG'	strain	Decreases	👶 Source Study
Escherichia coli D9	strain	Decreases	👶 Source Study
Escherichia coli DORA_A_5_14_21	strain	Decreases	👶 Source Study
Escherichia coli G3/10	strain	Decreases	👶 Source Study
Escherichia coli HS	strain	Decreases	👶 Source Study
Escherichia coli HVH 154 (4-5636698)	strain	Decreases	👶 Source Study
Escherichia coli HVH 175 (4-3405184)	strain	Decreases	👶 Source Study
Escherichia coli KO11FL	strain	Decreases	👶 Source Study
Escherichia coli M12	strain	Decreases	👶 Source Study
Escherichia coli M17	strain	Decreases	👶 Source Study
Escherichia coli M8	strain	Decreases	👶 Source Study
Escherichia coli MS 107-1	strain	Decreases	👶 Source Study
Escherichia coli MS 115-1	strain	Decreases	👶 Source Study
Escherichia coli Nissle 1917	strain	Decreases	👶 Source Study
Escherichia coli P12b	strain	Decreases	👶 Source Study
Escherichia coli PCN033	strain	Decreases	👶 Source Study
Escherichia coli STEC_DG131-3	strain	Decreases	👶 Source Study
Escherichia coli TW11917	strain	Decreases	👶 Source Study
Escherichia coli UMEA 3271-1	strain	Decreases	👶 Source Study
Escherichia coli UMN026	strain	Decreases	👶 Source Study	H00279 Uropathogenic Escherichia coli (UPEC) infection
Escherichia coli UTI89	strain	Decreases	👶 Source Study	H00279 Uropathogenic Escherichia coli (UPEC) infection
Phocaeicola vulgatus 274-1D4	strain	Decreases	👶 Source Study
Phocaeicola vulgatus CL09T03C04	strain	Decreases	👶 Source Study
Phocaeicola vulgatus dnLKV7	strain	Decreases	👶 Source Study
Phocaeicola vulgatus PC510	strain	Decreases	👶 Source Study
Phocaeicola vulgatus RJ2L3	strain	Decreases	👶 Source Study
Phocaeicola vulgatus str. 3775 SL(B) 10 (iv)	strain	Decreases	👶 Source Study
Phocaeicola vulgatus str. 3775 SR(B) 19	strain	Decreases	👶 Source Study
Phocaeicola vulgatus str. 3975 RP4	strain	Decreases	👶 Source Study
Bacteroides xylanisolvens XB1A	strain	Decreases	👶 Source Study
Escherichia coli APEC O2-211	strain	Decreases	👶 Source Study
Escherichia coli PMV-1	strain	Decreases	👶 Source Study
Bacteroides fragilis 638R	strain	Decreases	👶 Source Study	H02076 Bacteroides infection
Clostridium perfringens ATCC 13124	strain	Decreases	👶 Source Study	H00335 Foodborne Clostridium perfringens intoxication
Escherichia coli LF82	strain	Decreases	👶 Source Study	H00286 Crohn disease
Escherichia coli SE15	strain	Decreases	👶 Source Study
Bacteroides thetaiotaomicron VPI-5482	strain	Decreases	👶 Source Study
Clostridium perfringens F262	strain	Decreases	👶 Source Study
Phocaeicola vulgatus ATCC 8482	strain	Decreases	👶 Source Study
Clostridium perfringens str. 13	strain	Decreases	👶 Source Study	H00335 Foodborne Clostridium perfringens intoxication
Escherichia coli CFT073	strain	Decreases	👶 Source Study	H00279 Uropathogenic Escherichia coli (UPEC) infection
Bacteroides fragilis YCH46	strain	Decreases	👶 Source Study	H02076 Bacteroides infection
Clostridioides difficile ATCC 43255	strain	Decreases	👶 Source Study
Clostridioides difficile BI9	strain	Decreases	👶 Source Study
Clostridioides difficile QCD-23m63	strain	Decreases	👶 Source Study
Escherichia coli IHE3034	strain	Decreases	👶 Source Study	H01313 Escherichia coli meningitis
Escherichia coli E110019	strain	Decreases	👶 Source Study
Escherichia coli UM146	strain	Decreases	👶 Source Study	H00286 Crohn disease
Escherichia coli VR50	strain	Decreases	👶 Source Study
Clostridioides difficile QCD-37x79	strain	Decreases	👶 Source Study
Escherichia coli O169:H41	strain	Decreases	👶 Source Study
Escherichia coli O22:H8	strain	Decreases	👶 Source Study
Escherichia coli ATCC 8739	strain	Decreases	👶 Source Study
Escherichia coli O157:H16	strain	Decreases	👶 Source Study
Escherichia coli O178:H19	strain	Decreases	👶 Source Study
Clostridioides difficile QCD-63q42	strain	Decreases	👶 Source Study
Escherichia coli O15:H11	strain	Decreases	👶 Source Study
Escherichia coli SE11	strain	Decreases	👶 Source Study
Escherichia coli FAP1	strain	Decreases	👶 Source Study
Escherichia coli UMNF18	strain	Decreases	👶 Source Study
Escherichia coli K-12	strain	Decreases	👶 Source Study
Escherichia coli IAI39	strain	Decreases	👶 Source Study	H00279 Uropathogenic Escherichia coli (UPEC) infection
Escherichia coli APEC O1	strain	Decreases	👶 Source Study
Bacteroides ovatus V975	strain	Decreases	👶 Source Study
Bifidobacterium longum subsp. longum	subspecies	Decreases	👶 Source Study
Fusobacterium nucleatum subsp. nucleatum	subspecies	Decreases	📓 Source Study
Bifidobacterium longum subsp. infantis	subspecies	Decreases	👶 Source Study
Bifidobacterium longum subsp. suis	subspecies	Decreases	👶 Source Study
Lacticaseibacillus paracasei subsp. paracasei	subspecies	Decreases	👶 Source Study
Fusobacterium nucleatum subsp. nucleatum	subspecies	Decreases	👶 Source Study
Lacticaseibacillus paracasei subsp. tolerans	subspecies	Decreases	👶 Source Study
Bifidobacterium longum subsp. suillum	subspecies	Decreases	👶 Source Study

Impact of ketoconazole,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition	Positive Impact	Negative Impact	Benefit Ratio Impact
Abdominal Aortic Aneurysm	0.6		0.6
Acne		0.3	-0.3
ADHD	4.5	0.6	6.5
Age-Related Macular Degeneration and Glaucoma	1.1	0.4	1.75
Allergic Rhinitis (Hay Fever)	3.4	2.2	0.55
Allergies	6	3.1	0.94
Allergy to milk products	1.9	1.6	0.19
Alopecia (Hair Loss)	1.6		1.6
Alzheimer's disease	6.6	7.1	-0.08
Amyotrophic lateral sclerosis (ALS) Motor Neuron	3.7	0.9	3.11
Ankylosing spondylitis	4.5	1.8	1.5
Anorexia Nervosa	1.6	3.2	-1
Antiphospholipid syndrome (APS)	1.8	0.3	5
Asthma	5.8	2	1.9
Atherosclerosis	2.6	2	0.3
Atrial fibrillation	3.7	3	0.23
Autism	10	9.7	0.03
Autoimmune Disease	1.2	1	0.2
Barrett esophagus cancer	0.3	0.3	0
benign prostatic hyperplasia	0.6	0.3	1
Biofilm	2.3		2.3
Bipolar Disorder	2.4	1.4	0.71
Brain Trauma	0.9	1.4	-0.56
Breast Cancer	1		1
Cancer (General)	0.6	2.7	-3.5
Carcinoma	4.8	2.6	0.85
Celiac Disease	3.1	2.9	0.07
Cerebral Palsy	1.1	1.3	-0.18
Chronic Fatigue Syndrome	6	6.9	-0.15
Chronic Kidney Disease	4.7	2.8	0.68
Chronic Lyme	0.5	0.8	-0.6
Chronic Obstructive Pulmonary Disease (COPD)	2.7	1.7	0.59
Chronic Urticaria (Hives)	1.7	1.1	0.55
Coagulation / Micro clot triggering bacteria	1.9	1.3	0.46
Cognitive Function	2.5	1.6	0.56
Colorectal Cancer	7.1	2.8	1.54
Constipation	2	0.7	1.86
Coronary artery disease	2.9	2.6	0.12
COVID-19	10.2	13	-0.27
Crohn's Disease	10.4	6.2	0.68
Cushing's Syndrome (hypercortisolism)		0.8	-0.8
cystic fibrosis	1.2	1.9	-0.58
d-lactic acidosis (one form of brain fog)	0.6		0.6
deep vein thrombosis	2.5	1.4	0.79
Denture Wearers Oral Shifts	1.1		1.1
Depression	11.8	8.7	0.36
Dermatomyositis	0.3	0.3	0
Eczema	2.5	2.3	0.09
Endometriosis	3.5	2.3	0.52
Eosinophilic Esophagitis	0.3	0.3	0
Epilepsy	3.8	1.7	1.24
erectile dysfunction	1.4	0.3	3.67
Fibromyalgia	3.6	2.5	0.44
Functional constipation / chronic idiopathic constipation	6.1	4.7	0.3
gallstone disease (gsd)	4	1.1	2.64
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	1.8	1.2	0.5
Generalized anxiety disorder	3.3	1.4	1.36
giant cell arteritis		0.2	-0.2
Glioblastoma		0.3	-0.3
Gout	1.9	0.5	2.8
Graves' disease	1.6	3	-0.88
Gulf War Syndrome	0.9	1.2	-0.33
Halitosis	1.3	0.3	3.33
Hashimoto's thyroiditis	3.6	1.8	1
Heart Failure	5.1	1.8	1.83
hemorrhagic stroke	1.3		1.3
Hidradenitis Suppurativa	1.4		1.4
High Histamine/low DAO	1.9	0.6	2.17
hypercholesterolemia (High Cholesterol)	1.1		1.1
hyperglycemia	1.5	1.1	0.36
Hyperlipidemia (High Blood Fats)	0.9	0.3	2
hypersomnia		0.7	-0.7
hypertension (High Blood Pressure	4.7	5.2	-0.11
Hypothyroidism		1	-1
Hypoxia	3.5	0.3	10.67
IgA nephropathy (IgAN)	1.9	4.3	-1.26
Inflammatory Bowel Disease	9.2	9.4	-0.02
Insomnia	1.9	2.1	-0.11
Intelligence	1.9	0.6	2.17
Intracranial aneurysms	1.4	0.6	1.33
Irritable Bowel Syndrome	7.5	4.9	0.53
ischemic stroke	2.4	1.7	0.41
Liver Cirrhosis	7.3	3.9	0.87
Long COVID	7.3	8	-0.1
Low bone mineral density		1.1	-1.1
Lung Cancer	1.5	1	0.5
Lymphoma	0.6		0.6
Mast Cell Issues / mastitis	1.8	0.9	1
ME/CFS with IBS	0.9	2.4	-1.67
ME/CFS without IBS	2	2.4	-0.2
membranous nephropathy	0.3		0.3
Menopause	1.5	0.5	2
Metabolic Syndrome	8.4	7.3	0.15
Mood Disorders	10.5	7.5	0.4
multiple chemical sensitivity [MCS]	0.6	0.1	5
Multiple Sclerosis	6.8	6.8	0
Multiple system atrophy (MSA)	0.8	0.7	0.14
myasthenia gravis	0.9	0.7	0.29
neuropathic pain	0.3	3	-9
Neuropathy (all types)	0.7	2.2	-2.14
neuropsychiatric disorders (PANDAS, PANS)	1.2		1.2
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	6.3	4.2	0.5
NonCeliac Gluten Sensitivity	1.3	0.6	1.17
Obesity	10.9	8.5	0.28
obsessive-compulsive disorder	6.4	4.2	0.52
Osteoarthritis	3.2	1.8	0.78
Osteoporosis	2.2	1.3	0.69
pancreatic cancer	1	0.3	2.33
Parkinson's Disease	8.5	8.2	0.04
Polycystic ovary syndrome	7.8	3.2	1.44
Postural orthostatic tachycardia syndrome	0.2	0.6	-2
Premenstrual dysphoric disorder	0.7	0.4	0.75
primary biliary cholangitis	0.9	1.6	-0.78
Primary sclerosing cholangitis	1.9	3.2	-0.68
Psoriasis	3.5	3.3	0.06
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	8.3	4.3	0.93
Rosacea	1.2	0.7	0.71
Schizophrenia	5.7	2.8	1.04
scoliosis	0.9	1.2	-0.33
Sjögren syndrome	2.3	3.2	-0.39
Sleep Apnea	2.2	1.8	0.22
Slow gastric motility / Gastroparesis	1.2	0.3	3
Small Intestinal Bacterial Overgrowth (SIBO)	1.9	0	0
Stress / posttraumatic stress disorder	3.2	2.7	0.19
Systemic Lupus Erythematosus	4.5	2.3	0.96
Tic Disorder	1.4	1.7	-0.21
Tourette syndrome	0.9	0.3	2
Type 1 Diabetes	4.1	3.8	0.08
Type 2 Diabetes	10.1	7.2	0.4
Ulcerative colitis	6.3	6.9	-0.1
Unhealthy Ageing	5.9	2.4	1.46
Vitiligo	2.4	1.5	0.6

This is an Academic site. It generates theoretical models of what may benefit a specific microbiome results.

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