Anti-inflammatory: Hydrocortisone has potent anti-inflammatory properties, making it effective in reducing inflammation associated with various conditions such as allergic reactions, eczema, dermatitis, psoriasis, and insect bites.
Immunosuppression: Hydrocortisone suppresses the immune response, which can be beneficial in conditions where the immune system is overactive or attacking healthy tissues, such as autoimmune diseases like rheumatoid arthritis, lupus, and inflammatory bowel disease.
Antipruritic (anti-itch): Hydrocortisone relieves itching and discomfort associated with skin conditions like eczema, dermatitis, and insect bites by reducing inflammation and suppressing the release of inflammatory mediators.
Vasoconstriction: Hydrocortisone can cause vasoconstriction (narrowing of blood vessels), which helps to reduce swelling and redness in the affected area, contributing to its anti-inflammatory effects.
Antibacterial: In some formulations, hydrocortisone may be combined with antibacterial agents to treat skin infections or prevent secondary bacterial infections in conditions such as eczema or dermatitis.
Moisturizing: Certain hydrocortisone formulations may contain moisturizing ingredients that help hydrate the skin and maintain its barrier function, which can be beneficial in dry or irritated skin conditions.
Hormonal Regulation: Hydrocortisone is structurally similar to cortisol, a hormone produced by the adrenal glands. In cases of adrenal insufficiency or adrenal crisis, hydrocortisone may be used as a replacement therapy to restore hormonal balance.
Topical Use: Hydrocortisone is available in various topical formulations, including creams, ointments, lotions, gels, and foams, for application to the skin or mucous membranes. It is typically applied directly to the affected area, following the dosage and frequency recommended by a healthcare provider.
Systemic Use: In certain medical situations, hydrocortisone may be administered systemically, such as orally, intravenously, or by injection, to manage severe inflammatory or autoimmune conditions, adrenal insufficiency, or allergic reactions.
Side Effects: Prolonged or excessive use of hydrocortisone, especially at high doses or over large areas of the body, can lead to side effects such as skin thinning, skin discoloration, acne, delayed wound healing, and systemic effects including adrenal suppression, osteoporosis, hyperglycemia, and increased susceptibility to infections.
Impacted of hydrocortisone base,(prescription) On Probiotics
Rank
Probiotic
Impact
genus
Bifidobacterium
Reduces
species
Akkermansia muciniphila
Reduces
species
Bacteroides uniformis
Reduces
species
Bifidobacterium adolescentis
Reduces
species
Bifidobacterium longum
Reduces
species
Escherichia coli
Reduces
species
Lacticaseibacillus paracasei
Reduces
species
Parabacteroides distasonis
Reduces
subspecies
Bifidobacterium longum subsp. infantis
Reduces
subspecies
Bifidobacterium longum subsp. longum
Reduces
Bacteria Impacted by hydrocortisone base,(prescription)
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Impact of hydrocortisone base,(prescription) on Conditions from US National Library of Medicine
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups.
We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio: Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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