Asthma: Pranlukast is indicated for the prophylaxis and chronic treatment of asthma in adults and children. By blocking leukotriene receptors, pranlukast helps to reduce airway inflammation, bronchoconstriction, and mucus production, thereby improving breathing and reducing the frequency and severity of asthma symptoms such as coughing, wheezing, chest tightness, and shortness of breath.
Allergic Rhinitis: Pranlukast is also used for the treatment of allergic rhinitis, including seasonal and perennial allergic rhinitis. By inhibiting the effects of leukotrienes, pranlukast helps to alleviate symptoms such as nasal congestion, sneezing, runny or itchy nose, and nasal itching, associated with allergic reactions to environmental allergens such as pollen, dust mites, and pet dander.
Exercise-Induced Bronchoconstriction (EIB): Pranlukast may be used to prevent exercise-induced bronchoconstriction, a condition characterized by the narrowing of the airways following physical exertion. By blocking leukotriene receptors, pranlukast helps to prevent the bronchoconstriction and inflammation triggered by exercise, allowing individuals with asthma or exercise-induced bronchoconstriction to engage in physical activities more comfortably.
Chronic Obstructive Pulmonary Disease (COPD): While not typically a first-line treatment, pranlukast may be used as an adjunctive therapy in the management of chronic obstructive pulmonary disease (COPD), particularly in patients with features of asthma-COPD overlap syndrome (ACOS). By reducing airway inflammation and bronchoconstriction, pranlukast may help improve symptoms and lung function in some individuals with COPD.
Prevention of Respiratory Symptoms: Pranlukast may be prescribed to prevent respiratory symptoms triggered by exposure to allergens or other environmental factors known to induce asthma exacerbations or allergic reactions. By blocking leukotriene receptors, pranlukast helps to mitigate the inflammatory response in the airways, reducing the likelihood of symptom flare-ups.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Impact of pranlukast,(prescription) on Conditions from US National Library of Medicine
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups.
We just tally: X|reduces + Y|Increase = Positive β X|increases + Y|decrease = Negative.
Benefit Ratio: Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
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