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Hypertension (High Blood Pressure): Quinethazone is commonly prescribed to manage hypertension. As a diuretic, it works by increasing the excretion of sodium and water by the kidneys, leading to a decrease in blood volume and ultimately lowering blood pressure. By reducing the volume of fluid circulating in the blood vessels, it helps to decrease the workload on the heart and improve blood pressure control.
Edema: Quinethazone is also used to treat edema, which is the abnormal accumulation of fluid in the body's tissues, often manifested as swelling in the legs, feet, ankles, or abdomen. By promoting diuresis, quinethazone helps to remove excess fluid from the body, reducing swelling and relieving symptoms associated with edema.
Congestive Heart Failure: In cases of congestive heart failure, quinethazone may be prescribed as part of a treatment regimen to help reduce fluid retention and alleviate symptoms such as shortness of breath, fatigue, and swelling. By reducing fluid overload, it can help improve cardiac function and overall well-being in individuals with heart failure.
Nephrolithiasis (Kidney Stones): Thiazide diuretics like quinethazone can be used to prevent the formation of certain types of kidney stones by increasing the excretion of calcium in the urine. By reducing urinary calcium concentration, they can help to decrease the risk of stone formation in susceptible individuals.
Diabetes Insipidus: Quinethazone may be used in the management of diabetes insipidus, a condition characterized by excessive urination and thirst due to impaired regulation of fluid balance by the kidneys. By promoting diuresis and reducing urine output, it can help to alleviate symptoms and maintain fluid balance in patients with diabetes insipidus.
Off-label Uses: Quinethazone may also be prescribed off-label for other conditions, such as premenstrual syndrome (PMS), polycystic ovary syndrome (PCOS), and idiopathic hypercalciuria (excessive urinary calcium excretion). However, the evidence supporting its use for these indications may be limited, and its efficacy and safety should be carefully evaluated by a healthcare professional.
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
