Caldicellulosiruptor Details: NCBI 44000, gram-negative or unknown [genus]

| Caldicellulosiruptor| Caldicellulosiruptor Rainey et al. 1995 emend. Onyenwoke et al. 2006

1. Biotechnological applications: Caldicellulosiruptor species have attracted significant attention due to their potential applications in biotechnology, particularly in the bioconversion of lignocellulosic biomass into biofuels and other valuable products. Their robust cellulolytic and hemicellulolytic capabilities, coupled with their ability to grow at high temperatures (thermophiles), make them promising candidates for bioenergy production processes such as consolidated bioprocessing (CBP). CBP involves the simultaneous saccharification of biomass and fermentation of released sugars into biofuels using a single microorganism, thereby simplifying the production process and reducing costs.

2. Cellulose degradation: Caldicellulosiruptor species produce a range of cellulolytic enzymes, including cellulases, hemicellulases, and ligninases, which enable them to efficiently degrade plant biomass into fermentable sugars. These enzymes play a crucial role in the breakdown of cellulose and hemicellulose into smaller oligosaccharides and monosaccharides, which can then be metabolized by the bacteria for energy and growth. Understanding the cellulolytic machinery of Caldicellulosiruptor species may inform efforts to develop more efficient enzymatic cocktails for biomass conversion in industrial processes.

3. Thermophilic environments: Caldicellulosiruptor species are adapted to thrive in high-temperature environments, such as hot springs, geothermal vents, and compost piles, where they play important roles in the degradation of plant biomass. Their ability to withstand extreme temperatures and efficiently depolymerize complex carbohydrates under such conditions makes them valuable for industrial applications, especially in processes requiring elevated temperatures.

4. Bioremediation: Some Caldicellulosiruptor species have been explored for their potential in bioremediation, particularly in the degradation of lignocellulosic waste materials, such as agricultural residues, forestry by-products, and industrial waste streams. By converting recalcitrant biomass into simpler organic compounds, these bacteria can contribute to the remediation of contaminated sites and the reduction of environmental pollution.

5. Ecological roles: While Caldicellulosiruptor species are not typically associated with human health, they play important ecological roles in natural ecosystems, particularly in the degradation and recycling of plant biomass. By participating in the carbon cycle and nutrient cycling processes, these bacteria contribute to ecosystem functioning and stability.

Visuals of Interactions with other bacteria of the same rank

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Caldicellulosiruptor

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	1.46			5	3489	0	1455	263.4	90	608.1	0	510	0 %ile	100 %ile
biomesight	86.55	0	320	20	1660	0	1808	334.3	160	751.7	0	500	3.7 %ile	97.9 %ile
thorne	100			7	61	0	48	22.6	19	12.7	9	39	0 %ile	100 %ile
thryve	7.94	0	0	7	324	0	106	30	21	38.5	7	37	0 %ile	100 %ile

External Reference Ranges for Caldicellulosiruptor

Caldicellulosiruptor (NCBI 44000) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
PrecisionBiome	1.6339896319550462E-05	9.765207505552098E-05	0	0
Thorne (20/80%ile)	6.05	16.61	0.0006	0.0017

Statistic by Lab Source for Caldicellulosiruptor

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
BiomeSight	94.133 %	0.035 %	0.075 %	4380.0	4653
BiomeSightRdp	83.871 %	0.044 %	0.076 %	26.0	31
CerbaLab	66.667 %	0.002 %	0.001 %	2.0	3
custom	5.263 %	0.006 %	0.004 %	4.0	76
es-xenogene	18.75 %	0.02 %	0.014 %	6.0	32
Medivere	75 %	0.01 %	0.017 %	6.0	8
SequentiaBiotech	2.857 %	0.01 %	%	1.0	35
Thorne	89.965 %	0.001 %	0.001 %	260.0	289
Thryve	7.971 %	0.005 %	0.025 %	123.0	1543

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