Plasmodium chabaudi Details: NCBI 5825, gram-negative or unknown [species]

1. Model Organism for Malaria Research: P. chabaudi infection in mice closely mimics certain aspects of human malaria, making it a valuable model organism for studying the disease. Researchers use P. chabaudi infections in mice to investigate various aspects of malaria pathogenesis, host-parasite interactions, immune responses, and the efficacy of potential antimalarial drugs and vaccines.

2. Acute Malaria Infection: P. chabaudi infection in mice typically leads to an acute phase of malaria characterized by symptoms such as fever, anemia, weight loss, and lethargy. The severity of disease can vary depending on factors such as the parasite strain, infective dose, and mouse strain.

3. Chronic Infection and Relapses: In some cases, P. chabaudi infections in mice can result in chronic or persistent infections with periodic relapses of parasitemia. These relapses can occur weeks to months after the initial infection and may be associated with a resurgence of clinical symptoms.

4. Immunopathology and Immune Response: P. chabaudi infection induces complex host-parasite interactions that lead to immunopathological changes in infected mice. These include activation of the host immune response, production of pro-inflammatory cytokines, and development of adaptive immune responses against the parasite.

5. Drug and Vaccine Testing: The P. chabaudi model is commonly used to evaluate the efficacy of potential antimalarial drugs and vaccine candidates. Researchers use this model to assess the ability of new treatments to prevent or ameliorate malaria symptoms, reduce parasite burden, and promote host survival.

Visuals of Interactions with other bacteria of the same rank

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Plasmodium chabaudi

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	0.09			1	10	0	18	5.5	6	6.4	1	10	25 %ile	50 %ile

External Reference Ranges for Plasmodium chabaudi

Plasmodium chabaudi (NCBI 5825) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age

Statistic by Lab Source for Plasmodium chabaudi

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
custom	5.263 %	0.001 %	0.001 %	4.0	76

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