Heteroderidae Details: NCBI 6301, gram-negative or unknown [family]

1. Onchocerciasis (River Blindness): Onchocerciasis is caused by the filarial worm Onchocerca volvulus, which is transmitted to humans through the bites of black flies of the genus Simulium. The larvae of the worm migrate to the skin and eyes, leading to severe itching, skin lesions, and visual impairment, including blindness in some cases. Onchocerciasis is endemic in certain regions of Africa, Latin America, and Yemen.

2. Dermatitis: Onchocerciasis can cause severe itching and dermatitis due to the presence of microfilariae in the skin. This itching can be intense and persistent, leading to skin damage, ulceration, and secondary bacterial infections.

3. Ocular Lesions: Onchocerciasis can lead to various ocular manifestations, including punctate keratitis (inflammation of the cornea), sclerosing keratitis (scarring of the cornea), uveitis (inflammation of the uvea), and ultimately, optic nerve damage and blindness. These ocular complications can significantly impact the quality of life and productivity of affected individuals.

4. Subcutaneous Nodules: Onchocerciasis can cause the formation of subcutaneous nodules, which are localized swellings under the skin containing adult worms and inflammatory tissue. These nodules are typically painless but can cause discomfort and cosmetic concerns.

5. Systemic Symptoms: In addition to dermatological and ocular manifestations, onchocerciasis can cause systemic symptoms such as fever, lymphadenopathy (enlargement of lymph nodes), and general malaise.

Visuals of Interactions with other bacteria of the same rank

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Heteroderidae

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	0.04			0	2180			2180	2180		2180	2180	0 %ile	99 %ile

External Reference Ranges for Heteroderidae

Heteroderidae (NCBI 6301) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age

Statistic by Lab Source for Heteroderidae

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
es-xenogene	3.125 %	0.218 %	%	1.0	32

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