Roseburia intestinalis: NCBI 166486, [species]

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| DSM 14610| NCIMB 13810| Roseburia intestinalis| Roseburia intestinalis Duncan et al. 2002 emend. Duncan et al. 2006| strain L1-82

1. Butyrate Production: Roseburia intestinalis is an important butyrate producer. Butyrate, a short-chain fatty acid, serves as a vital energy source for the cells lining the colon (colonocytes) and contributes to maintaining gut barrier function and supporting a healthy gut environment.

2. Gut Health and Integrity: Butyrate produced by Roseburia intestinalis and other butyrate-producing bacteria plays a crucial role in promoting gut health. It helps nourish the cells lining the colon, stimulates mucus production, regulates the inflammatory response in the gut, and supports the maintenance of a healthy gut barrier.

3. Anti-inflammatory Properties: Butyrate has been shown to exhibit anti-inflammatory effects in the gut. By modulating immune responses and reducing the production of pro-inflammatory molecules, butyrate contributes to maintaining immune balance and mitigating inflammation in the gut.

4. Metabolic Health: Some studies suggest a potential link between Roseburia intestinalis and metabolic health. Higher abundance or activity of butyrate-producing bacteria like Roseburia intestinalis has been associated with improved metabolic parameters, such as glucose metabolism and insulin sensitivity.

5. Association with Dietary Fiber: Roseburia intestinalis thrives on dietary fibers that escape digestion in the small intestine. Consuming a diet rich in fiber and prebiotics supports the growth and activity of beneficial bacteria like Roseburia intestinalis.

6. Links to Gut Dysbiosis and Diseases: Alterations in the abundance or diversity of Roseburia intestinalis and other butyrate-producing bacteria have been observed in various conditions, including inflammatory bowel diseases (IBD), obesity, and metabolic disorders. However, the causal relationship and specific roles in disease development are still under investigation.

7. Potential Therapeutic Role: Some research suggests that interventions aimed at enhancing the abundance or activity of Roseburia intestinalis and other butyrate-producing bacteria might have therapeutic potential for improving gut health and managing certain digestive disorders.

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

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• The interactions are based on data from Biomesight. All relationships may not apply to other
• The size of the circles reflect the relative average count
• The width of the lines reflect the relative chi2 (significance)
• Green indicates increases/feed
• Red indicates decreases/reduces
• For an explanation of how these diagrams were obtained.

Roseburia intestinalis impacts on other bacteria of the same rank

Other bacteria of the same rank impacting Roseburia intestinalis