Legionella Details: NCBI 445, gram-negative or unknown [genus]

| Legionella| Legionella Brenner et al. 1979| Sarcobium| Sarcobium Drozanski 1991

1. Legionnaires' Disease:

   • Symptoms: Legionnaires' disease is a severe form of pneumonia with symptoms that include high fever, cough, shortness of breath, muscle aches, and headaches. Gastrointestinal symptoms may also occur.
   • Severity: Legionnaires' disease can be severe and may lead to complications, especially in individuals with weakened immune systems, the elderly, and those with underlying health conditions.
   • Transmission: The bacteria are transmitted to humans through the inhalation of aerosolized water droplets containing Legionella. Common sources include cooling towers, air conditioning systems, hot tubs, showers, and fountains.

2. Pontiac Fever:

   • Symptoms: Pontiac fever is a milder illness characterized by flu-like symptoms, including fever, muscle aches, and headaches. Gastrointestinal symptoms may also occur.
   • Severity: Pontiac fever is generally a self-limiting illness, and individuals usually recover without specific medical treatment.
   • Transmission: Similar to Legionnaires' disease, Pontiac fever is transmitted through the inhalation of aerosolized particles containing Legionella.

3. Amoebic Hosts:

   • Legionella species are known to replicate within amoebae, which can serve as hosts. This intracellular lifestyle within amoebae may contribute to the persistence of Legionella in aquatic environments.

4. Reservoirs:

   • Legionella species are commonly found in natural water sources, but they can proliferate in human-made water systems with warm temperatures, such as those used for air conditioning and industrial cooling.

5. Prevention:

   • Preventive measures include regular maintenance and cleaning of water systems, proper design and maintenance of cooling towers, and the use of disinfection methods to control Legionella growth.

6. Antibiotic Treatment:

   • Legionnaires' disease is treated with antibiotics, usually macrolides or quinolones. Early diagnosis and appropriate treatment are crucial for a positive outcome.

7. Public Health Concern:

   • Outbreaks of Legionnaires' disease have been associated with contaminated water systems in buildings, hotels, hospitals, and other facilities. Monitoring and management of water quality are essential for preventing outbreaks.

Visuals of Interactions with other bacteria of the same rank

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Legionella

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	1.06			3	500	0	304	72.8	23	118	0	114	0 %ile	100 %ile
biomesight	62.45	0	40	10	280	0	294	70.6	40	113.9	0	100	3.6 %ile	97.1 %ile
thorne	100			3	46	0	38	17.4	16	10.5	4	28	0 %ile	100 %ile
thryve	4.87	0	0	1	115	0	68	27.2	22	20.8	7	41	0 %ile	100 %ile
ubiome	0.13			0	17			17	17		17	17	0 %ile	99 %ile

External Reference Ranges for Legionella

Legionella (NCBI 445) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
PrecisionBiome	1.5186199561867397E-05	4.5138327550375834E-05	0	0
Thorne (20/80%ile)	3.78	8.52	0.0004	0.0009

Statistic by Lab Source for Legionella

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
BiomeSight	68.17 %	0.007 %	0.012 %	3204.0	4700
BiomeSightRdp	51.613 %	0.005 %	0.003 %	16.0	31
bugspeak	100 %	0.005 %	%	1.0	1
CerbaLab	66.667 %	0.001 %	0 %	2.0	3
custom	1.299 %	0.001 %	%	1.0	77
es-xenogene	15.625 %	0.024 %	0.018 %	5.0	32
Medivere	37.5 %	0.002 %	0.001 %	3.0	8
Thorne	89.456 %	0.001 %	0.001 %	263.0	294
Thryve	5.951 %	0.003 %	0.002 %	92.0	1546
uBiome	0.125 %	0.002 %	%	1.0	802
vitract	100 %	0.002 %	0.001 %	2.0	2

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Antibiotics, Antivirals etc	fluoroquinolone	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Honey {Honey }	1 Studies recorded. The consensus is Decreases👶, Click for details.

Food Groups Containing the Legionella bacteria

This is base on Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome. See that paper for details on foods groups.

1. dairy : 100% of Highest

Foods Containing the Legionella bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Beer Weight: 0.1696 Robiola di Roccaverano Cheese (Italy) Weight: 0.09701 tomato sour soup metagenome Weight: 0.0451 Liqvan cheese cheese Weight: 0.02937 Malaysian fermented fish sauce Weight: 0.02432 Sausage, Cyprus: Limassol Weight: 0.02115 Lard Farm Weight: 0.01163 Ham fermented for 4 years Weight: 0.007778 Chinese fish sauce Weight: 0.006886 Swiss-Dutch-type cheese Weight: 0.001406 yoghurt fermentation Weight: 0.0008667379800700497