Aggregatibacter Details: NCBI 416916, gram-negative or unknown [genus]

Found in Oral Cavity

For the possible significance see Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes, 2024

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| Aggregatibacter| Aggregatibacter Norskov-Lauritsen and Kilian 2006

1. Oral Pathogen: Aggregatibacter actinomycetemcomitans is considered an oral pathogen and is often associated with periodontal diseases. It can colonize the periodontal pockets around teeth and contribute to the development of periodontitis, a severe form of gum disease.

2. Periodontal Diseases: Aggregatibacter actinomycetemcomitans has been implicated in various periodontal diseases, including aggressive periodontitis. In aggressive periodontitis, there is a rapid loss of supporting structures around the teeth, leading to tooth mobility and potential tooth loss.

3. Endocarditis: While less common, Aggregatibacter actinomycetemcomitans has been associated with infective endocarditis, an infection of the heart valves. Individuals with pre-existing heart conditions may be at a higher risk.

4. Systemic Health: The presence of periodontal pathogens, including Aggregatibacter actinomycetemcomitans, has been studied in relation to systemic health. Some studies have explored potential links between periodontal diseases and conditions such as cardiovascular disease and diabetes. However, the nature of these associations is complex and may involve various factors.

5. Antibiotic Resistance: Some strains of Aggregatibacter actinomycetemcomitans may exhibit antibiotic resistance, which can impact treatment strategies for infections caused by this bacterium.

Visuals of Interactions with other bacteria of the same rank

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Aggregatibacter

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	1.24			5	4901	0	2061	260.2	32	918.7	7	225	0 %ile	100 %ile
biomesight	24.1	0	20	10	3120	0	2143	318.4	60	930.9	0	320	0 %ile	98.1 %ile
thorne	89.66			1	21417	0	9067	841.8	6	4196.7	0	24	0 %ile	100 %ile
thryve	16.52	0	9	1	4416	0	835	98.1	30	376.1	8	104	0 %ile	100 %ile
ubiome	21.67	0	24	18	18250	0	4976	802.4	135	2129.4	0	745	0 %ile	100 %ile

External Reference Ranges for Aggregatibacter

Aggregatibacter (NCBI 416916) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
PrecisionBiome	3.3341755624860525E-05	0.0015374453505501151	0	0
Thorne (20/80%ile)	2.2	7.68	0.0002	0.0008

Statistic by Lab Source for Aggregatibacter

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
AmericanGut	6.667 %	0.49 %	%	1.0	15
BiomeSight	25.591 %	0.033 %	0.128 %	1298.0	5072
BiomeSightRdp	45.161 %	0.004 %	0.005 %	14.0	31
CerbaLab	66.667 %	0.001 %	0 %	2.0	3
CosmosId	9.375 %	0.017 %	0.027 %	3.0	32
custom	7.692 %	0.001 %	0.001 %	6.0	78
es-xenogene	2.941 %	0.009 %	%	1.0	34
GutScan	28.571 %	0.001 %	0.001 %	4.0	14
Medivere	62.5 %	0.006 %	0.007 %	5.0	8
Precision	25 %	0.003 %	%	1.0	4
SequentiaBiotech	5.714 %	0.037 %	0.02 %	2.0	35
Thorne	75.649 %	0.01 %	0.14 %	233.0	308
Thryve	18.485 %	0.008 %	0.03 %	288.0	1558
uBiome	21.19 %	0.08 %	0.213 %	171.0	807
vitract	100 %	0.008 %	0.007 %	2.0	2

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Amino Acid and similar	Nattokinase {Natto}	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	amoxicillin [CFS]	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	azithromycin,[CFS]	2 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	ceftriaxone	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	clarithromycin [CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	doxycycline [CFS]	2 Studies recorded. The consensus is Decreases👪📓, Click for details.
Antibiotics, Antivirals etc	metronidazole [CFS]	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	minocycline [CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	moxifloxacin (antibiotic)	1 Studies recorded. The consensus is Decreases👪, Click for details.
Antibiotics, Antivirals etc	penicillin-moxalactam	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	streptomycin	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	tetracycline	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	dietary fiber	1 Studies recorded. The consensus is Decreases👪, Click for details.
Diet Style	Fiber, total dietary	1 Studies recorded. The consensus is Decreases👪, Click for details.
Diet Style	high-fat diets	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	High-fibre diet {Whole food diet}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Diet Style	Slow digestible carbohydrates. {Low Glycemic}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Drug or "Non-drug"	Methylene blue	1 Studies recorded. The consensus is Decreases👪, Click for details.
Flavonoids, Polyphenols etc	2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one {Luteolin}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Flavonoids, Polyphenols etc	Humulus lupulus compound {Xanthohumol}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	Coriandrum sativum {Coriander}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	fruit	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	fruit/legume fibre	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	Hericium erinaceus {Lion's Mane Mushroom }	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Hydrastis canadensis {Goldenseal}	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	kefir	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Myristica fragrans {Nutmeg}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	Propolis {Bee glue}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	Prunus mume {Umeboshi}	2 Studies recorded. The consensus is Decreases👶👪, Click for details.
Food (excluding seasonings)	Rheum × hybridum {Rhubarb}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	Ribes nigrum {black currant}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	Sulforaphane {Dark Greens}	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Tea tree	1 Studies recorded. The consensus is Decreases👪, Click for details.
Food (excluding seasonings)	Vaccinium {Cranberry}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium {Berberine}	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	allium sativum {garlic}	3 Studies recorded. The consensus is Decreases👶👪📓, Click for details.
Herb or Spice	Boswellia serrata {Boswellia}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	Cinnamomum zeylanicum {Ceylon Cinnamon}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Cymbopogon citratus {Lemongrass}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Diferuloylmethane {Curcumin}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	Larrea tridentata {Chaparral}	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	Lavandula angustifolia {lavender}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Menta × piperita {peppermint}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Metha family {Mint}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Moringa Oleifera	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	Nigella sativa {black cumin}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	Perilla frutescens {Perilla}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	Pimpinella anisum {Anise}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Herb or Spice	Thymus vulgaris {thyme}	2 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	Pistacia lentiscus {mastic gum}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Prescription - Other	proton-pump inhibitors (prescription)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bacillus	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bacillus subtilis natto {B.natto}	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bacillus,lactobacillus,streptococcus,saccharomyces probiotic	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bifidobacterium	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bifidobacterium longum {B.Longum }	1 Studies recorded. The consensus is Decreases👪, Click for details.
Probiotics	Bifidobacterium longum subsp. longum BB536 {BB536}	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	Lacticaseibacillus paracasei {L.paracasei}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Probiotics	Lacticaseibacillus rhamnosus {l. rhamnosus}	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	lactobacillus acidophilus {L. acidophilus}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Probiotics	lactobacillus helveticus,lactobacillus rhamnosus	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	Lactobacillus plantarum {L. plantarum}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics	Lentilactobacillus kefiri {Kefibios}	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	Ligilactobacillus salivarius {L. salivarius}	1 Studies recorded. The consensus is Decreases👶, Click for details.
Sugar and similar	ß-(1?4)-linked D-glucosamine and N-acetyl-D-glucosamine {Chitosan}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Vitamins, Minerals and similar	Silver nanoparticles {Colloidal silver}	1 Studies recorded. The consensus is Decreases👪, Click for details.
Vitamins, Minerals and similar	vitamin d	1 Studies recorded. The consensus is Decreases📓, Click for details.

Food Groups Containing the Aggregatibacter bacteria

This is base on Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome. See that paper for details on foods groups.

1. fermented_fruits_and_vegetables : 100% of Highest
2. dairy : 0.0410783% of Highest

Foods Containing the Aggregatibacter bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Passito wine Weight: 0.06238 Mozzarella cheese Weight: 0.005761